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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.4
- 수록면
- 566 - 566 (1page)
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Malonyl CoA is an important building block for the production of diverse value-added chemicals including natural products, but competition of target compounds limits the intracellular malonyl-CoA availability. For high throughput screening of targets that that increase the malonyl-CoA pool, diverse malonyl CoA sensors have been developed. However, there have limitations, including narrow applicable strain range, only in Escherichia coli and Saccharomyces cerevisiae and requirements of signal transduction multi-steps. Here, we report novel colorimetric malonyl-CoA biosensor for industrially important bacteria: Corynebacterium glutamicum, Pseudomonas putida, and Escherichia coli. RppA is a type III polyketide synthase producing colored metabolites flaviolin that was developed as mal ... 전체 초록 보기
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