지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 제27권 제6호
- 발행연도
- 2004.1
- 수록면
- 581 - 588 (8page)
이용수
초록· 키워드
오류제보하기
A series of 2, 5-dihydroxychalcones and related compounds were synthesized, and their cyto-toxicities against tumor cell lines and human umbilical venous endothelial cells (HUVEC） eval-uated. It was found that chalcones, with electron-withdrawing substituents on an A ring, exhibited significant cytotoxicities. Among the synthesized compounds, 2'-chlbro-2, 5-dihydrox-ychalcone (9） was most potent, with an $IC_{50}$ value as low as $0.31{\;}{\mu\textrm{g}}/mL$. This compound also exhibited a significant cytotoxic selectivity toward HUVEC.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
한국 Streptomyces SP.로부터 분리한 방향족 화합물과 지질 화합물의 세포독성 연구
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
1997 .01
-
Synthesis, Cytotoxicity and Antitumor Activity of 2,3-Diarylcyclopent-2-ene-1-ones
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2002 .01
-
Synthesis, Biological Activity and Comparative Analysis of Cytotoxicities and Human Topoisomerase I Inhibitory Activities of Isoquinoline Compounds
대한약학회 학술대회
2001 .01
-
Biodistribution of Micro-/Nano-sized Particles and Their Cytotoxicity
대한치과재료학회 학술대회
2011 .05
-
Synthesis of 〔1,2,5〕thiadiazole-1,1-dioxides and their cytotoxicities
대한약학회 학술대회
2000 .01
-
Synthesis and Cytotoxicity of Some Rigid Derivatives of Methyl 2,5-Dihydroxycinnamate
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2002 .01
-
5-Arylidene-2(5H)-Furanone Derivatives: Synthesis and Structure-Activity Relationship for Cytotoxicity
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
-
Synthesis of 6-Aziridinylbenzimidazole Derivatives and Their In Vitro Antitumor Activities
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1998 .01
-
Six new dammarane-type triterpene saponins from Panax ginseng flower buds and their cytotoxicity
Journal of Ginseng Research
2020 .03
-
Monoterpenoid계의 새로운 항암제 합성 및 In vitro 세포독성 평가
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2001 .01
-
2-(1-Hydroxyiminoalkyl)-1,4-dimethoxy-9,10-anthraquinones: Synthesis and Evaluation of Cytotoxicity
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2000 .01
-
Evaluation of the Extraction Method for the Cytotoxicity Testing of Latex Gloves
Yonsei Medical Journal
2005 .01
-
종양괴사인자 세포독성에서 항산화제의 효과
Tuberculosis and Respiratory Diseases
1999 .01
-
Development of a cell-based model to screen the potential toxicity of chemical compounds
한국실험동물학회 학술발표대회 논문집
2020 .07
-
Chalcone 유도체들의 사람 유방암세포주 및 사람 섬유육종 세포에 대한 세포독성효과
약학회지
2010 .01
-
Synthesis and In Vitro Cytotoxicity of 1-Azanthraquinone-3-Carboxamides
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1999 .01
-
Synthesis, Cytotoxicity and Structure-Activity Relationship Study of Terpyridines
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2006 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0