지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 317 - 322 (6page)
이용수
초록· 키워드
오류제보하기
Hepatic fibrosis is one of chronic liver diseases which spread in worldwide and it has high risk to turn advanced cirrhosis and hepatocellualr carcinoma. Brassica family has been produced for commercial purpose and in Korea Brassica rapa (Turnip) is cultivated in Ganghwa County, Gyeonggi-do Korea and used for making Kimchi. Recently pharmacological effects of turnip have been known; diabete mellitus modulation, alcohol oxidization, and fibrosis inhibition. In previous study we found antifibrogenic effect of turnip water extract and in this study we made turnip nanoparticle to promote turnip delivery into liver. At the same time we assessed the biological safety of turnip nanoparticle. Thioacetamide (TAA) induced hepatic nodular formation and fibrosis (mean of fibrosis score: 4). However, 1% turnip nanoparticle inhibited TAA-induced hepatic nodular formation and fibrosis (mean of fibrosis score: 2-3). Activities of serum enzymes (aspartic acid transaminase (AST), alanine transaminase (ALT), and total bilirubin (T-Bil)), complete blood count (CBC), and the appearance of organs were not different from control and 1% turnip nanoparticle treatment. Conclusively 1% turnip nanoparticle significantly reduced TAA-induced hepatic fibrosis and was safe in 7-weeks feeding.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Anti-hepatofibrogenic Effect of Turnip Water Extract on Thioacetamide-induced Liver Fibrosis
Laboratory Animal Research
2010 .03
-
Inhibitory Effect of Turnip Extract Fractions on Hepatic Fibrogenesis
Laboratory Animal Research
2006 .09
-
Turnip Attenuates Progression of Thioacetamide-Induced Liver Fibrogenesis
한국실험동물학회 학술발표대회 논문집
2005 .06
-
Inhibitory Effect of Turnip Powder on Thioacetamide-induced Rat Hepatic Fibrogenesis
한국실험동물학회 학술발표대회 논문집
2009 .04
-
Evaluation of disease severity using multimodal MR imaging in hepatic fibrosis animal model
한국실험동물학회 학술발표대회 논문집
2019 .07
-
Validation of P2/MS for reflecting hepatic fibrosis in patients with hepatocellular carcinoma
Clinical and Molecular Hepatology
2010 .01
-
Suppressive Effects of Platycodon grandiflorum on the Progress of Carbon Tetrachloride-Induced Hepatic Fibrosis
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
-
Hepatitis Virus Induced Hepatic Inflammation and Fibrosis
한국간담췌외과학회 학술대회지
2014 .04
-
Magnetization-tagged MRI is a simple method for predicting liver fibrosis
Clinical and Molecular Hepatology
2016 .01
-
Non-alcoholic Fatty Liver Disease (NAFLD) and Significant Hepatic Fibrosis Defined by Non-invasive Assessment in Patients with Type 2 Diabetes
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Sinusoidal Endothelial Cell and Hepatic Fibrosis
한국간담췌외과학회 학술대회지
2014 .04
-
Noninvasive Assessment of Advanced Fibrosis Based on Hepatic Volume in Patients with Nonalcoholic Fatty Liver Disease
Gut and Liver
2017 .01
-
Effects of HepacureⓇ on Dmn Induced Hepatic Fibrosis in Rat
한국실험동물학회 학술발표대회 논문집
2004 .06
-
Therapeutic effects of Shibashin Misena® against fine-dust-induced pulmonary disorders in mice
한국실험동물학회 학술발표대회 논문집
2020 .02
-
Simple Tests to Predict Hepatic Fibrosis in Nonalcoholic Chronic Liver Diseases
Gut and Liver
2007 .01
-
Protective effects of Lipoic acid complex on CCl4-induced hepatic fibrosis in Sprague-Dawley rats
한국실험동물학회 학술발표대회 논문집
2005 .06
-
식도 정맥류 출혈을 동반한 간섬유증 1례
Pediatric Gastroenterology, Hepatology & Nutrition
2004 .01
-
천연식물추출물(RIP)이 쥐의 간섬유화 치료에 미치는 영향
기초간호자연과학회지
2006 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0