Changes in Diagnostic Methods for Pulmonary Tuberculosis between 2005 and 2013

Ahn, Bin; Kim, Joohae; Yoo, Chul-Gyu; Kim, Young Whan; Han, Sung Koo; Yim, Jae-Joon

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자료유형: 학술저널

저자정보: Ahn, Bin (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine) Kim, Joohae (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine) Yoo, Chul-Gyu (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine) Kim, Young Whan (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine) Han, Sung Koo (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine) Yim, Jae-Joon (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine)

저널정보: 대한결핵 및 호흡기학회 Tuberculosis and Respiratory Diseases 결핵 및 호흡기 질환 제78권 제3호

발행연도: 2015.1

수록면: 227 - 231 (5page)

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Background: Diagnostic methods for pulmonary tuberculosis (TB) have recently advanced. The aim of this study was to evaluate the changes in TB diagnostic tests that prompted the initiation of anti-TB treatment over time in South Korea, an industrialized country with an intermediate TB burden. Methods: Patients diagnosed with pulmonary TB in the first halves of 2005 and 2013 at a tertiary referral hospital were included. Diagnostic methods that prompted the initiation of anti-TB treatment were compared between the 2 groups of patients. Results: A greater proportion of patients were diagnosed with pulmonary TB using bronchoscopy in 2013 than in 2005 (26.7% vs. 6.6%, respectively; p<0.001), while the proportion of patients clinically diagnosed with pulmonary TB was lower in 2013 than in 2005 (24.7% vs. 49.0%, respectively; p<0.001). Additionally, more patients started anti-TB treatment based on positive polymerase chain reaction (PCR) results for Mycobacterium tuberculosis DNA in 2013 than in 2005 (47.3% vs. 7.9%, respectively; p<0.001). Conclusion: The initiation of treatment for pulmonary TB in South Korea has become more frequently based on PCR and the use of bronchoscopic specimens.

#Tuberculosis #Pulmonary #Diagnosis #Bronchoscopy #Nucleic Acid Amplification Techniques

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