지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제17권 제3호
- 발행연도
- 2016.1
- 수록면
- 1,325 - 1,332 (8page)
이용수
초록· 키워드
오류제보하기
Radioprotective effects of ginger essential oil (GEO) on mortality, body weight alteration, hematological parameters, antioxidant status and chromosomal damage were studied in irradiated mice. Regression analysis of survival data in mice exposed to radiation yielded LD50/30 as 7.12 and 10.14 Gy for control (irradiation alone) and experimental (GEO-treated irradiated) mice, respectively, with a dose reduction factor (DRF) of 1.42. In mice exposed to whole-body gamma-irradiation (6 Gy), GEO pre-treatment at 100 and 500 mg/kg b.wt (orally) significantly ameliorated decreased hematological and immunological parameters. Radiation induced reduction in intestinal tissue antioxidant enzyme levels such as superoxide dismutase, catalase, glutathione peroxidase and glutathione was also reversed following administration of GEO. Tissue architecture of small intestine which was damaged following irradiation was improved upon administration of GEO. Anticlastogenic effects of GEO were studied by micronuclei assay, chromosomal aberration and alkaline gel electrophoresis assay. GEO significantly decreased the formation of micronuclei, increased the P/N ratio, inhibited the formation of chromosomal aberrations and protected agaisnt cellular DNA damage in bone marrow cells as revealed by comet assay. These results are supportive of use of GEO as a potential radioprotective compound.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Establishment of a mouse model of 70% lethal dose by total-body irradiation
한국실험동물학회 학술발표대회 논문집
2016 .08
-
High-dose rate γ-irradiation leads to the change of body and organ weights, hematological parameters, frequency of micronuclei in ICR mice
한국실험동물학회 학술발표대회 논문집
2016 .08
-
Panax ginseng Meyer prevents radiation-induced liver injury via modulation of oxidative stress and apoptosis
Journal of Ginseng Research
2017 .04
-
Dose Estimation Curves Following In Vitro X-ray Irradiation Using Blood From Four Healthy Korean Individuals
Annals of Laboratory Medicine
2019 .01
-
Steamed ginger extract ameliorates alcohol-induced liver injury in mice via modulation of inflammatory response and oxidative stress
한국실험동물학회 학술발표대회 논문집
2019 .07
-
Toxicity Bioassay in BALB/c mice exposed to low dose rate radiation- Changes in body and organ weights, hematological parameters, and histological parameters of BALB/c mice exposed to low-dose-rate gamma radiation
한국실험동물학회 학술발표대회 논문집
2016 .02
-
Celecoxib, a selective cyclooxygenase-2 inhibitor, aggravates radiation-induced intestinal damage in mice
Journal of Biomedical and Translational Research
2021 .01
-
Differences in whole body irradiation susceptibility according to the strains and age of mice
한국실험동물학회 학술발표대회 논문집
2015 .02
-
Low-dose-rate irradiation induces the expression changes of apoptosis-associated genes
한국실험동물학회 학술발표대회 논문집
2016 .08
-
From breeding mouse to editing mouse genome
한국실험동물학회 학술발표대회 논문집
2017 .08
-
Comparison of the Antioxidant Activities of Various Processed Fruits and Vegetables in APAP-induced Oxidative Stress in BALB/c Mice
대한의생명과학회지
2019 .09
-
식이유도 비만 마우스에서 칸나비디올(Cannabidiol) 오일의 체중 감량 효과에 대한 검증연구
신경정신의학
2022 .11
-
Evaluation of low dose administration of N-methyl-N-nitrosourea to p53 heterozygous knockout mouse
한국실험동물학회 학술발표대회 논문집
2021 .07
-
Re-Irradiation for Recurrent Gliomas: Treatment Outcomes and Prognostic Factors
Yonsei Medical Journal
2016 .01
-
Antioxidant effects of Phloroglucinol on gamma radiation-induced oxidative stress on mice skin
예방수의학회지
2017 .03
-
Peripheral Blood Lymphocytes as In Vitro Model to Evaluate Genomic Instability Caused by Low Dose Radiation
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Evaluation of urethane-induced lung tumor in p53 heterozygous null mice for a short-term carcinogenicity study
한국실험동물학회 학술발표대회 논문집
2021 .01
-
Development of a Test Method for the Evaluation of DNA Damage in Mouse Spermatogonial Stem Cells
Toxicological Research
2017 .04
-
Phenotype difference in aged C57BL/6 and 129 mice
한국실험동물학회 학술발표대회 논문집
2021 .07
-
Development of a Wide Dose-Rate Range Electron Beam Irradiation System for Pre-Clinical Studies and Multi-Purpose Applications Using a Research Linear Accelerator
의학물리
2020 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0