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논문 기본 정보

자료유형
학술저널
저자정보
Koh, Geon (Department of Nuclear Medicine, Gachon University Gil Hospital) Hwang, Kyung Hoon (Department of Nuclear Medicine, Gachon University Gil Hospital) Lee, Haejun (Department of Nuclear Medicine, Gachon University Gil Hospital) Kim, Seog Gyun (Department of Nuclear Medicine, Gachon University Gil Hospital) Lee, Beom Koo (Department of Orthopedics, Gachon University Gil Hospital)
저널정보
대한핵의학회 Nuclear medicine and molecular imaging : NMMI Nuclear medicine and molecular imaging : NMMI 제50권 제2호
발행연도
2016.1
수록면
137 - 143 (7page)

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Purpose To determine whether treatment response in patients with knee pain could be predicted using uptake patterns on single-photon emission computed tomography/computed tomography (SPECT/CT) images. Methods Ninety-five patients with knee pain who had undergone SPECT/CT were included in this retrospective study. Subjects were divided into three groups: increased focal uptake (FTU), increased irregular tracer uptake (ITU), and no tracer uptake (NTU). A numeric rating scale (NRS-11) assessed pain intensity. We analyzed the association between uptake patterns and treatment response using Pearson's chisquare test and Fisher's exact test. Uptake was quantified from SPECT/CT with region of interest (ROI) counting, and an intraclass correlation coefficient (ICC) calculated agreement. We used Student's t-test to calculate statistically significant differences of counts between groups and the Pearson correlation to measure the relationship between counts and initial NRS-1k1. Multivariate logistic regression analysis determined which variables were significantly associated with uptake. Results The FTU group included 32 patients; ITU, 39; and NTU, 24. With conservative management, 64 % of patients with increased tracer uptake (TU, both focal and irregular) and 36 % with NTU showed positive response. Conservative treatment response of FTU was better than NTU, but did not differ from that of ITU. Conservative treatment response of TU was significantly different from that of NTU (OR 3.1; p=0.036). Moderate positive correlation was observed between ITU and initial NRS-11. Age and initial NRS-11 significantly predicted uptake. Conclusions Patients with uptake in their knee(s) on SPECT/CT showed positive treatment response under conservative treatment.
#Knee #Pain #SPECT #Uptake #Response

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참고문헌 (23)

참고문헌 신청
Calmbach WL / 2003 / Evaluation of patients presenting with knee pain: Part I. History, physical examination, radiographs, and laboratory tests / Am Fam Physician 68:907~912 google schola Calmbach WL / 2003 / Evaluation of patients presenting with knee pain: Part II. Differential diagnosis / Am Fam Physician 68:917~922 google schola Ha S / 2015 / Comparison of SPECT/CT and MRI in diagnosing symptomatic lesions in ankle and foot pain patients: diagnostic performance and relation to lesion type / PLoS ONE 10:e0117583 google schola Papathanassiou D / 2009 / Single-photon emission computed tomography combined with computed tomography(SPECT/CT)in bone diseases / Joint Bone Spine 76:474~480 google schola Sharma P / 2013 / Hybrid SPECT-CT for characterizing isolated vertebral lesions observed by bone scintigraphy : comparison with planar scintigraphy, SPECT, and CT / Diagn Interv Radiol 19:33~40 google schola

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