지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 346 - 349 (4page)
이용수
초록· 키워드
오류제보하기
Objective : To investigate the value of lumbar bone mineral density (BMD) in fracture risk assessment (FRAX) tool. Methods : One hundred and ten patients aged over 60 years were enrolled and divided into 2 groups as non-osteoporotic vertebral fracture (OVF) and OVF groups. The 10-year-risk of major osteoporotic vertebral fracture of each group was calculated by FRAX tool with femoral and lumbar spine BMDs to compare the usefulness of lumbar spine BMD in prediction of OVF. The blood level of osteocalcin and C-terminal telopeptide (CTX) as markers of activities of osteoblast and osteoclast, respectively were analyzed using the institutional database. Results : In the OVF group, the ratio of patients with previous fracture history or use of glucocorticoid was higher than those in non-OVF group (p=0.000 and 0.030, respectively). The levels of T-score of femur neck and lumbar spine in OVF group were significantly lower than those in non-OVF group (p=0.001 and 0.000, respectively). The risk of OVF in FRAX using femur BMD in non-OVF and OVF groups was $6.7{\pm}6.13$ and $11.4{\pm}10.06$, respectively (p=0.007). The risk of using lumbar BMD in the 2 groups was $6.9{\pm}8.91$ and $15.1{\pm}15.08$, respectively (p=0.002). The areas under the receiver operator characteristic curve in the FRAX risk with lumbar and femur neck BMD were 0.726 and 0.684, respectively. The comparison of osteocalcin and CTX was not significant (p=0.162 and 0.369, respectively). Conclusion : In our study, the 10-year risk of major osteoporotic fracture in the OVF group of our study was lower than the recommended threshold of intervention for osteoporosis. Hence, a lower threshold for the treatment of osteoporosis may be set for the Korean population to prevent OVF. In the prediction of symptomatic OVF, FRAX tool using lumbar spine BMD may be more useful than that using femur neck BMD.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Chin DK. / 2007 / Prevalence of osteoporosis in patients requiring spine surgery : incidence and significance of osteoporosis in spine disease / Osteoporos Int 18:1219~1224
Dontas IA. / 2007 / Risk factors and prevention of osteoporosis-related fractures / J Musculoskelet Neuronal Interact 7:268~272
El Maghraoui A. / 2008 / DXA scanning in clinical practice / QJM 101:605~617
El Maghraoui A. / 2014 / The discriminative ability of FRAX, the WHO algorithm, to identify women with prevalent asymptomatic vertebral fractures : a cross-sectional study / BMC Musculoskelet Disord 15:365
Fink HA. / 2005 / What proportion of incident radiographic vertebral deformities is clinically diagnosed and vice versa? / J Bone Miner Res 20:1216~1222
Dontas IA. / 2007 / Risk factors and prevention of osteoporosis-related fractures / J Musculoskelet Neuronal Interact 7:268~272
El Maghraoui A. / 2008 / DXA scanning in clinical practice / QJM 101:605~617
El Maghraoui A. / 2014 / The discriminative ability of FRAX, the WHO algorithm, to identify women with prevalent asymptomatic vertebral fractures : a cross-sectional study / BMC Musculoskelet Disord 15:365
Fink HA. / 2005 / What proportion of incident radiographic vertebral deformities is clinically diagnosed and vice versa? / J Bone Miner Res 20:1216~1222
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Management of Osteoporotic Vertebral Fracture: Review Update 2022
Asian Spine Journal
2022 .12
-
Parkinson's Disease as Risk Factor in Osteoporosis and Osteoporotic Vertebral Fracture : Prevalence Study Using National Inpatient Sample Database in Korea
대한신경외과학회지
2019 .01
-
Occurrence of vertebral fracture more closely associated with decreased anteroposterior than lateral lumbar bone mineral density
Osteoporosis and Sarcopenia
2016 .01
-
Osteoporotic Fracture Risk Assessment Using Bone Mineral Density in Korean: A Community-based Cohort Study
대한골대사학회지
2016 .01
-
Change of Bone Mineral Density Measurement among Patients with Osteoporotic Fractures in Korean Population Using National Claim Database
대한골대사학회지
2017 .08
-
Low Predictive Value of FRAX Adjusted by Trabecular Bone Score for Osteoporotic Fractures in Korean Women: A Community-Based Cohort Study
Endocrinology and Metabolism
2020 .01
-
Factors Affecting Bone Mineral Density Measurement after Fracture in South Korea
대한골대사학회지
2017 .01
-
Vertebral Augmentation: State of the Art
Asian Spine Journal
2016 .01
-
Osteoporotic Fracture: 2015 Position Statement of the Korean Society for Bone and Mineral Research
대한골대사학회지
2015 .01
-
Application of Machine Learning Algorithms to Predict Osteoporotic Fractures in Women
Korean Journal of Family Medicine
2024 .05
-
Proximal Femoral Geometry as Fracture Risk Factor in Female Patients with Osteoporotic Hip Fracture
대한골대사학회지
2016 .01
-
A FRAX Experience in Korea: Fracture Risk Probabilities with a Country-specific Versus a Surrogate Model
대한골대사학회지
2015 .01
-
The optimal cut-off values of FRAX without BMD for predicting osteoporosis fracture risk in the older adults at Nan, Thailand
Osteoporosis and Sarcopenia
2024 .03
-
Clinical Characteristics of Primary and Secondary Osteoporotic Fractures: Data from Single Referral Center Emergency Department
대한골대사학회지
2019 .01
-
What Is the Effect of Spino-Pelvic Sagittal Parameters and Back Muscles on Osteoporotic Vertebral Fracture?
Asian Spine Journal
2015 .04
-
Is ankle fracture related to low bone mineral density and subsequent fracture? A systematic review
Osteoporosis and Sarcopenia
2020 .01
-
The Relationship between Renal Function and Bone Marrow Density in Healthy Korean Women
대한폐경학회지
2017 .08
-
Intervention thresholds to identify postmenopausal women with high fracture risk: A single center study based on the Philippines FRAX model
Osteoporosis and Sarcopenia
2021 .09
-
Relationship between Type 2 Diabetes Mellitus and Lumbar Bone Mineral Density in Postmenopausal Women
Asian Spine Journal
2021 .12
-
Korean Guideline for the Prevention and Treatment of Glucocorticoid-induced Osteoporosis
대한골대사학회지
2018 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0