지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
오류제보하기
Background: To develop guidelines and recommendations to prevent and treat glucocorticoid (GC)-induced osteoporosis (GIOP) in Korea. Methods: The Korean Society for Bone and Mineral Research and the Korean College of Rheumatology have developed this guideline based on Guidance for the Development of Clinical Practice Guidelines ver. 1.0 established by the National Evidence-Based Healthcare Collaborating Agency. This guideline was developed by adapting previously published guidelines, and a systematic review and quality assessment were performed. Results: This guideline applies to adults aged ≥19 years who are using or plan to use GCs. It does not include children and adolescents. An initial assessment of fracture risk should be performed within 6 months of initial GC use. Fracture risk should be estimated using the fracture-risk assessment tool (FRAX) after adjustments for GC dose, history of osteoporotic fractures, and bone mineral density (BMD) results. All patients administered with prednisolone or an equivalent medication at a dose ≥2.5 mg/day for ≥3 months are recommended to use adequate calcium and vitamin D during treatment. Patients showing a moderate-to-high fracture risk should be treated with additional medication for osteoporosis. All patients continuing GC therapy should undergo annual BMD testing, vertebral X-ray, and fracture risk assessment using FRAX. When treatment failure is suspected, switching to another drug should be considered. Conclusions: This guideline is intended to guide clinicians in the prevention and treatment of GIOP.
목차
등록된 정보가 없습니다.
참고문헌 (78)
참고문헌 신청
Saag KG / 1994 / Low dose long-term corticosteroid therapy in rheumatoid arthritis: an analysis of serious adverse events / Am J Med 96:115~123
Lane NE / 1998 / The science and therapy of glucocorticoid-induced bone loss / Endocrinol Metab Clin North Am 27:465~483
Van Staa TP / 2003 / Bone density threshold and other predictors of vertebral fracture in patients receiving oral glucocorticoid therapy / Arthritis Rheum 48:3224~3229
Steinbuch M / 2004 / Oral glucocorticoid use is associated with an increased risk of fracture / Osteoporos Int 15:323~328
Angeli A / 2006 / High prevalence of asymptomatic vertebral fractures in post-menopausal women receiving chronic glucocorticoid therapy: a cross-sectional outpatient study / Bone 39:253~259
Lane NE / 1998 / The science and therapy of glucocorticoid-induced bone loss / Endocrinol Metab Clin North Am 27:465~483
Van Staa TP / 2003 / Bone density threshold and other predictors of vertebral fracture in patients receiving oral glucocorticoid therapy / Arthritis Rheum 48:3224~3229
Steinbuch M / 2004 / Oral glucocorticoid use is associated with an increased risk of fracture / Osteoporos Int 15:323~328
Angeli A / 2006 / High prevalence of asymptomatic vertebral fractures in post-menopausal women receiving chronic glucocorticoid therapy: a cross-sectional outpatient study / Bone 39:253~259
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