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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 691 - 699 (9page)
이용수
초록· 키워드
오류제보하기
Objective : Lumbar discectomy is an effective treatment for lumbar disc herniation (LDH); however, up to 2-18% of patients with LDH have experienced recurrent disc herniation. The purpose of this study was to evaluate the efficacy of a novel annular closure device (ACD) for preventing LDH recurrence and re-operation compared with that of conventional lumbar discectomy (CLD). Methods : In this prospective randomized controlled trial, we compared CLD with discectomy utilizing the $Barricaid^{(R)}$ (Intrinsic Therapeutics, Inc., Woburn, MA, USA) ACD. Primary radiologic outcomes included disc height, percentage of preoperative disc height maintained, and re-herniation rates. Additional clinical outcomes included visual analog scale (VAS) scores for back and leg pain, Oswestry Disability Index (ODI) scores, and 12-item short-form health survey (SF-12) quality of life scores. Outcomes were measured at preoperation and at 1 week, 1, 3, 6, 12, and 24 months postoperation. Results : Sixty patients (30 CLD, 30 ACD) were enrolled in this study. At 24-month follow-up, the disc height in the ACD group was significantly greater than that in the CLD group ($11.4{\pm}1.5$ vs. $10.2{\pm}1.2mm$, p=0.006). Re-herniation occurred in one patient in the ACD group versus six patients in the CLD group (${\chi}^2=4.04$, p=0.044). Back and leg VAS scores, ODI scores, and SF-12 scores improved significantly in both groups compared with preoperative scores in the first 7 days following surgery and remained at significantly improved levels at a 24-month follow-up. However, no statistical difference was found between the two groups. Conclusion : Lumbar discectomy with the $Barricaid^{(R)}$ (Intrinsic Therapeutics, Inc.) ACD is more effective at maintaining disc height and preventing re-herniation compared with conventional discectomy. Our results suggest that adoption of ACD in lumbar discectomy can help improve the treatment outcome.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Bouma GJ / 2013 / The high-risk discectomy patient: prevention of reherniation in patients with large anular defects using an anular closure device / Eur Spine J 22:1030~1036
Brazier JE / 1992 / Validating the SF-36 health survey questionnaire: new outcome measure for primary care / BMJ 305:160~164
Carragee EJ / 2003 / Clinical outcomes after lumbar discectomy for sciatica: the effects of fragment type and anular competence / J Bone Joint Surg Am 85:102~108
Carragee EJ / 2006 / A prospective controlled study of limited versus subtotal posterior discectomy: shortterm outcomes in patients with herniated lumbar intervertebral discs and large posterior anular defect / Spine (Phila Pa 1976) 31:653~657
Davis RA / 1994 / A long-term outcome analysis of 984 surgically treated herniated lumbar discs / J Neurosurg 80:415~421
Brazier JE / 1992 / Validating the SF-36 health survey questionnaire: new outcome measure for primary care / BMJ 305:160~164
Carragee EJ / 2003 / Clinical outcomes after lumbar discectomy for sciatica: the effects of fragment type and anular competence / J Bone Joint Surg Am 85:102~108
Carragee EJ / 2006 / A prospective controlled study of limited versus subtotal posterior discectomy: shortterm outcomes in patients with herniated lumbar intervertebral discs and large posterior anular defect / Spine (Phila Pa 1976) 31:653~657
Davis RA / 1994 / A long-term outcome analysis of 984 surgically treated herniated lumbar discs / J Neurosurg 80:415~421
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