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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 493 - 497 (5page)
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초록· 키워드
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From the n-BuOH soluble fraction of the leaves of Salix hulteni, six compounds were isolated as aldose reductase inhibitors. On the basis of spectral data, these compounds were identified as diosmetin-7-O-${\beta}$-D-glucoside (1), isoquercitrin (2), diosmetin-7-O-${\beta}$-D-xylosyl-(1${\rightarrow}$6)-${\beta}$-D-glucoside (3), aromadendrin-3-O-${\beta}$-D-glucoside (4), astragalin (5), and p-hydroxyacetophenone glucoside (6). All of the isolates were evaluated in vitro for inhibitory activity against the aldose reductase. Of these, compounds 1-5 exhibited inhibitory activity against aldose reductase with $IC_{50}$ values ranging 1.4 to 5.8 ${\mu}M$.
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