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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 379 - 384 (6page)
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초록· 키워드
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Objective : Mechanical thrombectomy (MT) for acute intracranial internal carotid artery (ICA) occlusion is often complicated by difficult revascularization and non-involved territory embolization possibly related with larger clot-burden. This study aims to evaluate the efficacy of proximal aspiration thrombectomy (PAT) using a balloon-tipped guide catheter for clot-burden reduction in such cases with period-to-period analysis (period 1 : standard MT without PAT; period 2 : PAT first, then standard MT for the remaining occlusion). Methods : Eighty-six patients who underwent MT for acute intracranial ICA occlusion were included in this analysis from the prospectively maintained stroke registry (33 patients in period 1 and 53 in period 2). In period 2, 'responder' was defined as a case where some amount of clot was retrieved by PAT and the following angiography showed partial or full recanalization. Results : Fifteen of fifty-three patients in period 2 (28.3%) were 'responders' to PAT. There was a significantly higher incidence of atrial fibrillation in the 'responder' subgroup. Period 2 showed a significantly shorter puncture-to-reperfusion time (94.5 minutes vs. 56.0 minutes; p=0.002), a significantly higher Thrombolysis in Cerebral Infarction of 2b-3 reperfusion (45.5% vs. 73.6%; p=0.009), but only a trend for better 3-month favorable outcome (mRS 0-2; 36.4% vs. 54.7%; p=0.097). There was no increase in the incidence of procedure-related complications or intracranial hemorrhage in period 2. Conclusion : A strategy of PAT before standard MT may result in shorter puncture-to-reperfusion time and better angiographic outcome than a strategy of standard MT for acute intracranial ICA occlusion.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Barreto AD / 2008 / Thrombus burden is associated with clinical outcome after intra-arterial therapy for acute ischemic stroke / Stroke 39:3231~3235
Bhatia R / 2010 / Low rates of acute recanalization with intravenous recombinant tissue plasminogen activator in ischemic stroke : real-world experience and a call for action / Stroke 41:2254~2258
Eesa M / 2012 / Manual aspiration thrombectomy through balloon-tipped guide catheter for rapid clot burden reduction in endovascular therapy for ICA L/T occlusion / Neuroradiology 54:1261~1265
Gralla J / 2008 / Occlusion length is a crucial determinant of efficiency and complication rate in thrombectomy for acute ischemic stroke / AJNR Am J Neuroradiol 29:247~252
Higashida RT / 2003 / Trial design and reporting standards for intra-arterial cerebral thrombolysis for acute ischemic stroke / Stroke 34:e109~e137
Bhatia R / 2010 / Low rates of acute recanalization with intravenous recombinant tissue plasminogen activator in ischemic stroke : real-world experience and a call for action / Stroke 41:2254~2258
Eesa M / 2012 / Manual aspiration thrombectomy through balloon-tipped guide catheter for rapid clot burden reduction in endovascular therapy for ICA L/T occlusion / Neuroradiology 54:1261~1265
Gralla J / 2008 / Occlusion length is a crucial determinant of efficiency and complication rate in thrombectomy for acute ischemic stroke / AJNR Am J Neuroradiol 29:247~252
Higashida RT / 2003 / Trial design and reporting standards for intra-arterial cerebral thrombolysis for acute ischemic stroke / Stroke 34:e109~e137
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