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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 12 - 18 (7page)
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Skin is an emerging target tissue in pharmaceutical and cosmetic science. Safety assessment for dermal toxicity is a critical step for development of topically applicable pharmaceutical agents and ingredients in cosmetics. Urgent needs exist to set up toxicity testing methods for dermal safety, and identification of novel biomarkers for pathological cutaneous alteration is highly required. Here we will discuss if vascular endothelial growth factor (VEGF) has a potential as a biomarker for dermal impairment. Experimental and clinical evidences for induction of keratinocytic VEGF under pathological conditions will be reviewed.
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등록된 정보가 없습니다.
참고문헌 (86)
참고문헌 신청
Alitalo, A. K. / 2013 / VEGF-C and VEGF-D blockade inhibits inflammatory skin carcinogenesis / Cancer Res 73:4212~4221
Bernard, F. X. / 2012 / Keratinocytes under fire of proinflammatory cytokines: Bona fide innate immune cells involved in the physiopathology of chronic atopic dermatitis and psoriasis / J. Allergy (Cairo) :718725
Ballaun, C. / 1995 / Human keratinocytes express the three major splice forms of vascular endothelial growth factor / J. Invest. Dermatol 104:7~10
Bhushan, M. / 1999 / Levels of endothelial cell stimulating angiogenesis factor and vascular endothelial growth factor are elevated in psoriasis / Br. J. Dermatol 141:1054~1060
Blaudschun, R. / 2000 / The first peak of the UVB irradiationdependent biphasic induction of vascular endothelial growth factor (VEGF) is due to phosphorylation of the epidermal growth factor receptor and independent of autocrine transforming growth factor alpha / FEBS Lett 474:195~200
Bernard, F. X. / 2012 / Keratinocytes under fire of proinflammatory cytokines: Bona fide innate immune cells involved in the physiopathology of chronic atopic dermatitis and psoriasis / J. Allergy (Cairo) :718725
Ballaun, C. / 1995 / Human keratinocytes express the three major splice forms of vascular endothelial growth factor / J. Invest. Dermatol 104:7~10
Bhushan, M. / 1999 / Levels of endothelial cell stimulating angiogenesis factor and vascular endothelial growth factor are elevated in psoriasis / Br. J. Dermatol 141:1054~1060
Blaudschun, R. / 2000 / The first peak of the UVB irradiationdependent biphasic induction of vascular endothelial growth factor (VEGF) is due to phosphorylation of the epidermal growth factor receptor and independent of autocrine transforming growth factor alpha / FEBS Lett 474:195~200
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