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자료유형
학술저널
저자정보
Bae, Eun-Kyong (School of Biological Sciences and Bio-health Products Research Center, Inje University) Kim, Na-Ri (School of Biological Sciences and Bio-health Products Research Center, Inje University) Yun, Mi-Jung (School of Biological Sciences and Bio-health Products Research Center, Inje University) Youn, Hyong-Chol (School of Biological Sciences, Seoul National University) Youn, Kyung-Joon (School of Biological Sciences, Seoul National University) Lee, Kang-Ro (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University) Youn, Hyun-Joo (School of Biological Sciences and Bio-health Products Research Center, Inje University)
저널정보
한국응용약물학회 Biomolecules & Therapeutics(구 응용약물학회지) Biomolecules & therapeutics 제16권 제4호
발행연도
2008.1
수록면
403 - 409 (7page)

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Eclipta prostrata grows abundantly in the tropical and the sub-tropical parts of the world including most part of the Korean Peninsula. The plant has been traditionally used for the treatment of a number of inflammatory diseases including hepatitis and enteritis but the nature of its immuno-modulating activity needs more studies. In this study, water-soluble sugar-containing fractions were purified from the herb and their effects on the culture of mouse splenocytes were examined. One of the fractions significantly suppressed apoptosis of the splenocytes in culture, which involves the gene expression regulation of a number of cytokines and cytokine receptors including MIP1-$\beta$. This study could explain an immunological activity of Eclipta prostrata and would lead to identify an immuno-active compound from the plant.

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