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논문 기본 정보

자료유형
학술저널
저자정보
Son, Hye Joo (Department of Nuclear Medicine, Dong-A University Medical Center, Dong-A University College of Medicine) Jeong, Young Jin (Department of Nuclear Medicine, Dong-A University Medical Center, Dong-A University College of Medicine) Yoon, Hyun Jin (Department of Nuclear Medicine, Dong-A University Medical Center, Dong-A University College of Medicine) Wang, Lih (Department of Orthopedic Surgery, Dong-A University Medical Center, Dong-A University College of Medicine) Kim, Hyeon Jun (Department of Orthopedic Surgery, Dong-A University Medical Center, Dong-A University College of Medicine) Park, Jong-Hwan (Institute of Convergence Bio-Health, Dong-A University) Kang, Do-Young (Department of Nuclear Medicine, Dong-A University Medical Center, Dong-A University College of Medicine)
저널정보
대한핵의학회 Nuclear medicine and molecular imaging : NMMI Nuclear medicine and molecular imaging : NMMI 제50권 제4호
발행연도
2016.1
수록면
308 - 321 (14page)

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Purpose We investigated the visual tracer distribution pattern and serial changes in uptake ratio in different anatomical zones during the natural postoperative course in order to establish a reference for evaluation of patients with complications. Methods A total of 36 patients without symptoms after hip or knee arthroplasty were grouped according to the interval between surgery and the scan. The serial changes in SUVmean in each periprosthetic zone were quantified using the volume of interest isocontour method. Images were classified according to the uptake distribution pattern. The uptake ratios in the postoperative period groups were then compared using the Kruskal-Wallis test. The correlation between uptake ratio and postoperative period was then determined. Results Tracer distribution patterns in hip prostheses were classified into three types and the patterns in knee prostheses into five types. In hip prostheses, intense osteoblastic activity was observed during 3-6 months and then declined in most patients, but showed a slight increase over 15-25 months in 5-10 % of patients. The correlation coefficients varied among the zones. Significant differences in uptake ratios among the period groups was found for all zones, except zone 8. Porous coated areas showed higher uptake than uncoated areas only for the period the 3-6 months. In knee prostheses, uptake ratios showed a curvilinear pattern, increasing from 3-6 to 8-15 months and declining later. The uptake ratios were different among the period groups. Every zone showed a positive correlation from 3-6 to 8-15 months, and negative correlations from 8-15 to 22-25 months. Conclusions This is the first $^{18}F$-sodium fluoride PET/CT study investigating the stability of implants and sets a reference for evaluation of patients with complications.

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