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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 479 - 482 (4page)
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We report a case of a 31-year-old woman with glioblastoma multiforme (GBM) in the pineal region with associated leptomeningeal dissemination and lumbar metastasis. The patient presented with severe headache and vomiting. Magnetic resonance imaging (MRI) of the brain showed a heterogeneously enhanced tumor in the pineal region with obstructive hydrocephalus. After an urgent ventricular-peritoneal shunt, she was treated by subtotal resection and chemotherapy concomitant with radiotherapy. Two months after surgery, MRI showed no changes in the residual tumor but leptomeningeal dissemination surrounding the brainstem. One month later, she exhibited severe lumbago and bilateral leg pain. Thoracico-lumbar MRI showed drop like metastasis in the lumbar region. Finally she died five months after the initial diagnosis. Neurosurgeons should pay attention to GBM in the pineal region, not only as an important differential diagnosis among the pineal tumors, but due to the aggressive features of leptomeningeal dissemination and spinal metastasis.
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참고문헌 (21)
참고문헌 신청
Amini A. / 2006 / Glioblastoma multiforme of the pineal region / J Neurooncol 79:307~314
Birbilis TA. / 2010 / Spinal metastasis of glioblastoma multiforme : an uncommon suspect? / Spine (Phila Pa 1976) 35:E264~E269
Bradfield JS. / 1972 / Pineal tumors and ectopic pinealomas. Analysis of treatment and failures / Radiology 103:399~406
Cho BK. / 1998 / Pineal tumors : experience with 48 cases over 10 years / Childs Nerv Syst 14:53~58
Edwards MS. / 1988 / Pineal region tumors in children / J Neurosurg 68:689~697
Birbilis TA. / 2010 / Spinal metastasis of glioblastoma multiforme : an uncommon suspect? / Spine (Phila Pa 1976) 35:E264~E269
Bradfield JS. / 1972 / Pineal tumors and ectopic pinealomas. Analysis of treatment and failures / Radiology 103:399~406
Cho BK. / 1998 / Pineal tumors : experience with 48 cases over 10 years / Childs Nerv Syst 14:53~58
Edwards MS. / 1988 / Pineal region tumors in children / J Neurosurg 68:689~697
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