접촉성 육아종에서 양성자 펌프 억제제의 치료 효과

김동환; 김건호; 정선민; 송창면; 지용배; 태경

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자료유형: 학술저널

저자정보: 김동환 (한양대학교 의과대학 이비인후-두경부외과학교실) 김건호 (한양대학교 의과대학 이비인후-두경부외과학교실) 정선민 (한양대학교 의과대학 이비인후-두경부외과학교실) 송창면 (한양대학교 의과대학 이비인후-두경부외과학교실) 지용배 (한양대학교 의과대학 이비인후-두경부외과학교실) 태경 (한양대학교 의과대학 이비인후-두경부외과학교실)

저널정보: 대한후두음성언어의학회 대한후두음성언어의학회지 대한후두음성언어의학회지 제28권 제2호

발행연도: 2017.1

수록면: 123 - 127 (5page)

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연구배경

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연구방법

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연구결과

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Background and Objectives : Contact granuloma is granulation tissue that occurs mainly in the vocal process of arytenoid cartilage. Among several etiological factors, gastric acid reflux is known to be an important cause. The aim of this study was to evaluate clinical characteristics of contact granuloma and analyze the effectiveness of proton pump inhibitor in the treatment of contact granuloma. Materials and Methods : We retrospectively reviewed the medical records of 40 patients who were treated with proton pump inhibitor (PPI) for contact granuloma from January 2011 to December 2015. Reflux finding score (RFS), reflux symptom index (RSI) and size of granuloma were evaluated before and after treatment serially to assess the effectiveness of proton pump inhibitor. Results : Of 40 patients, 25 patients (62.5%) and 10 patients (25%) showed improvement and partial improvement of granuloma, respectively. Five patients showed no response. The mean times of partial improvement and improvement were $2.08{\pm}2.23$ months and $4.60{\pm}2.77$ months, respectively and mean duration of PPI treatment was $6.8{\pm}5.2$ months. Conclusion : Proton pump inhibitors is effective in the treatment of contact granuloma.

#접촉성 육아종 #양성자 펌프 억제제 #인후두 역류 #위식도 역류

참고문헌 (17)

참고문헌 신청

Hoffman HT / 2001 / Vocal process granuloma / Head Neck 23(12):1061~1074

Lee SW / 2014 / Comparison of Treatment Modalities for Contact Granuloma: A Nationwide Multicenter Study / Laryngoscope 124:1187~1191

Ylitalo R / 1999 / A retrospective study of contact granuloma / Laryngoscope 109:433~436

Carroll TL / 2010 / Vocal process granuloma and glottal insufficiency: an overlooked etiology? / Laryngoscope 120:114~120

Havas TE / 1999 / A management strategy for vocal process granulomas / Laryngoscope 109:301~306

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