지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 제31권 제7호
- 발행연도
- 2008.1
- 수록면
- 938 - 944 (7page)
이용수
초록· 키워드
오류제보하기
Interaction of a drug with other drugs and dietary supplements is becoming an emerging issue for patients and health insurance authorities due to awareness of adverse drug event. In this study, we examined the effects of coenzyme Q10 (CoQ10), one of the most popular dietary supplements, on the pharmacokinetic parameters of theophylline in rats. The pharmacokinetic parameters of theophylline changed significantly when the drug was administered after five consecutive days of pretreatment with CoQ10. Time to reach maximum plasma concentration of theophylline delayed when the drug was administered after the pretreatment with CoQ10. Maximum plasma concentration and area under the curve of theophylline were about two-fold increased and other pharmacokinetic parameters such as half-life and volume of distribution were also changed significantly. Therefore, although CoQ10 is generally considered a safe dietary supplement, it appears that patients on theophylline therapy should use caution when they take CoQ10.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Overview about the Safety and Function of $CoQ_{10}$
한국응용약물학회 추계학술발표논문집
2006 .01
-
Coenzyme Q: a progress towards the treatment of neurodegenerative disease
Oriental pharmacy and experimental medicine
2010 .01
-
Microbial production of coenzyme Q10
한국응용약물학회 추계학술발표논문집
2006 .01
-
생약제제의 약물동태 연구 및 상호작용
한국임상약학회지
2010 .01
-
High Performance Liquid Chromatographic Analysis of Rabeprazole in Human Plasma and its Pharmacokinetic Application
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2008 .01
-
Safety, High Quality, Confidence of Kaneka CoQ10
한국응용약물학회 추계학술발표논문집
2006 .01
-
Pharmacokinetic Changes in Drugs during Protein-Calorie Malnutrition： Correlation between Drug Metabolism and Hepatic Microsomal Cytochrome P450 Isozymes
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
-
The effect of coenzyme Q10 on endothelial function in a young population
Physical therapy rehabilitation science
2012 .01
-
Clinical Significance of Pharmacokinetic Evaluation
대한임상약리학회 심포지움
1993 .01
-
Pharmacokinetic and Pharmacodynamic Analysis of CNS Drugs
대한약학회 학술대회
2005 .01
-
Development of physiological pharmacokinetic model
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1987 .01
-
Pharmacokinetic-Pharmacodynamic Relationships Under Non-controlled Conditions. Disease-Drug Interactions
한국응용약물학회 추계학술발표논문집
2002 .01
-
Pharmacokinetics and metabolism of new anti-ulcer drug KR60436
대한약학회 학술대회
2000 .01
-
Medicinal plants and phytochemicals for diabetes mellitus: pharmacokinetic characteristics and herb‑drug interactions
Journal of Pharmaceutical Investigation
2019 .01
-
Pharmacokinetics after Gastrectomy
대한외과학회 학술대회 초록집
2019 .10
-
약물상호작용의 원리와 의의
생물정신의학
2000 .01
-
Effect of Hepatic Cirrhosis on the Pharmacokinetics of Theophylline in Rats
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1997 .01
-
항생제 Fluoroquinolones의 약동학 및 약력학에 관한 최신 정보
Urogenital Tract Infection
2015 .01
-
약물상호작용 : 기분안정제와 항불안제
생물정신의학
2000 .01
-
신생아중환자의 약동학적 다양성에 영향을 미치는 요인
한국임상약학회지
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0