The effect of coenzyme Q10 on endothelial function in a young population

Petrofsky, Jerrold; Laymon, M.; Lee, H.; Hernandez, E.; Dequine, D.; Thorsen, L.; Lovell, R.; Andrade, J.

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자료유형: 학술저널

저자정보: Petrofsky, Jerrold (Department of Physical Therapy, Azusa Pacific University) Laymon, M. (Department of Physical Therapy, Azusa Pacific University) Lee, H. (Department of Physical Therapy, Loma Linda University) Hernandez, E. (Department of Physical Therapy, Azusa Pacific University) Dequine, D. (Department of Physical Therapy, Azusa Pacific University) Thorsen, L. (Department of Physical Therapy, Azusa Pacific University) Lovell, R. (Department of Physical Therapy, Azusa Pacific University) Andrade, J. (Department of Physical Therapy, Azusa Pacific University)

저널정보: 물리치료재활과학회 Physical therapy rehabilitation science Physical therapy rehabilitation science 제1권 제1호

발행연도: 2012.1

수록면: 6 - 12 (7page)

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Objective: Coenzyme (CoQ10) is an enzymatic co factor used in normal cellular metabolism. Recent evidence shows that in people with heart disease it can reverse endothelial cell damage in the blood vessels. It is also a potent antioxidant. Design: One group pretest-posttest design. Methods: In the present study, endothelial function was evaluated using the response to occlusion and heat before and 2 weeks after administration of CoQ10, 300 mg/day. Thirty Eight subjects, who are physical therapy students, participated in a series of experiments to see if taking 300 mg of CoQ10 daily for 2 weeks would impact resting blood flow in the forearm skin and the blood flow response to 4 minutes of vascular occlusion and the response to local heat ($42^{\circ}C$) for 6 minutes. Results: The results showed that, for this population, there was no difference in the response to heat. However, the response to occlusion was improved after administration of CoQ10. Conclusions: It would appear that in a young population CoQ10 has no effect on the nitric oxide vasodilator pathway in skin but does influence other vasodilator pathways.

#Blood flow #Circulation #Flow mediated dilation #Q10 #Vitamins

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이 논문의 저자 정보

Petrofsky, Jerrold

소속기관 Department of Physical Therapy, School of Allied Health Professions, Loma Linda University

주요연구분야 의약학 > 임상의학 > 물리치료학

논문수 4 이용수 3

Laymon, M.

소속기관 Department of Physical Therapy, Loma Linda University

주요연구분야 의약학 > 임상의학 > 물리치료학

논문수 2 이용수 3

Lee, H.

소속기관 Department of Physical Therapy, Loma Linda University

주요연구분야 의약학 > 임상의학 > 물리치료학

논문수 1 이용수 3

Hernandez, E.