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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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초록· 키워드
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Several 8-cycloalkoxychrysin analogs were synthesized from 6-benzyloxy-5,8-dihydroxyflavone and cycloalkanols in 2 steps and we evaluated their inhibitory activities against NO production from LPS-induced RAW 264.7 cells. Among tested analogs, two analogs with cyclopentyl substructure (796 and 798) showed strong inhibitory activity against NO production.
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참고문헌 (13)
참고문헌 신청
Hecker, M / 1996 / Inhibition by antioxidants of nitric oxide synthase expression in murine macrophages: role of nuclear factor kappa B and interferon regulatory factor 1 / Br. J. Pharmacol 118:2178
Pearce, F. L / 1984 / Mucosal mast cells. III. Effect of quercetin and other flavonoids on antigeninduced histamine secretion from rat intestinal mast cells / J. Allergy Clin. Immunol 73:819
Fishkin, R. J / 1997 / Endotoxin-induced reduction of social investigation by mice: interation with amphetamine and anti-inflammatory drugs / Psychopharmacol 132:335
Habtemariam, S / 1997 / Flavonoids as inhibitors or enhancers of the cytotoxicity of tumor necrosis factor-a in L-929 tumor cells / J. Nat. Prod 60:775
Liang, Y.-C / 2001 / Supression of inducible cyclooxygenase and nitric oxide synthase through activation of peroxisome proliferatoractivated receptor-g by flavonoids in mouse macrophages / FEBS Lett 496:12
Pearce, F. L / 1984 / Mucosal mast cells. III. Effect of quercetin and other flavonoids on antigeninduced histamine secretion from rat intestinal mast cells / J. Allergy Clin. Immunol 73:819
Fishkin, R. J / 1997 / Endotoxin-induced reduction of social investigation by mice: interation with amphetamine and anti-inflammatory drugs / Psychopharmacol 132:335
Habtemariam, S / 1997 / Flavonoids as inhibitors or enhancers of the cytotoxicity of tumor necrosis factor-a in L-929 tumor cells / J. Nat. Prod 60:775
Liang, Y.-C / 2001 / Supression of inducible cyclooxygenase and nitric oxide synthase through activation of peroxisome proliferatoractivated receptor-g by flavonoids in mouse macrophages / FEBS Lett 496:12
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