지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.8
- 수록면
- 356 - 368 (13page)
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초록· 키워드
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Purpose: Histidine-containing dipeptides, which are rich in chicken, have been reported to reduce the risk of metabolic abnormalities via anticarbonylation mechanism in animal models. To determine the effect of dietary histidine-containing dipeptides on metabolic risk factors in humans, the relation between chicken consumption and insulin resistance were determined in a population consuming high carbohydrate and low protein.
Methods: A total of 7,183 subjects (2,929 men and 4,254 women) aged ≥ 50 years from the Korea National Health and Nutrition Examination Survey (KNHANES) were divided into three groups according to chicken consumption (rarely, monthly, and weekly), and evaluated for the metabolic risk factors using homeostasis model assessment for insulin resistance (HOMA-IR) and quantitative insulin sensitivity check index (QUICKI) in this cross-sectional study. The fourth and fifth (IV-1–3 & V-1) KNHANES, which had blood insulin data, were chosen for the current study.
Results: The chicken consumption was significantly associated with insulin (p for trend = 0.018) and HOMA-IR (p for trend = 0.023) in men. In particular, the ‘weekly’ chicken consuming men in the lowest tertile (< 65.0%) of carbohydrate intake group had significantly lower HOMA-IR (p for trend = 0.033) and higher QUICKI (p for trend = 0.043) than the ‘rarely’ intake group. In addition, the odds ratio for abnormal HOMA-IR was 0.55 (95% confidence interval [CI], 0.31–0.99) and QUICKI was 0.47 (95% CI, 0.26–0.86) for the ‘weekly’ chicken consuming group.
Conclusion: The ‘weekly’ chicken consumption had a beneficial effect on insulin resistance and it may partially be due to the major bioactive components in chicken, histidinecontaining dipeptides.
Methods: A total of 7,183 subjects (2,929 men and 4,254 women) aged ≥ 50 years from the Korea National Health and Nutrition Examination Survey (KNHANES) were divided into three groups according to chicken consumption (rarely, monthly, and weekly), and evaluated for the metabolic risk factors using homeostasis model assessment for insulin resistance (HOMA-IR) and quantitative insulin sensitivity check index (QUICKI) in this cross-sectional study. The fourth and fifth (IV-1–3 & V-1) KNHANES, which had blood insulin data, were chosen for the current study.
Results: The chicken consumption was significantly associated with insulin (p for trend = 0.018) and HOMA-IR (p for trend = 0.023) in men. In particular, the ‘weekly’ chicken consuming men in the lowest tertile (< 65.0%) of carbohydrate intake group had significantly lower HOMA-IR (p for trend = 0.033) and higher QUICKI (p for trend = 0.043) than the ‘rarely’ intake group. In addition, the odds ratio for abnormal HOMA-IR was 0.55 (95% confidence interval [CI], 0.31–0.99) and QUICKI was 0.47 (95% CI, 0.26–0.86) for the ‘weekly’ chicken consuming group.
Conclusion: The ‘weekly’ chicken consumption had a beneficial effect on insulin resistance and it may partially be due to the major bioactive components in chicken, histidinecontaining dipeptides.
목차
ABSTRACT
INTRODUCTION
METHODS
RESULTS
DISCUSSION
SUMMARY
REFERENCES
참고문헌 (48)
참고문헌 신청
Ford ES / 2008 / Metabolic syndrome and risk of incident diabetes : findings from the European prospective investigation into cancer and nutrition-Potsdam study / Cardiovasc Diabetol 7(1):35
Meigs JB / 2007 / Impact of insulin resistance on risk of type 2 diabetes and cardiovascular disease in people with metabolic syndrome / Diabetes Care 30(5):1219~1225
Martínez-Augustin O / 2012 / Bioactive anti-obesity food components / Int J Vitam Nutr Res 82(3):148~156
Abete I / 2011 / Obesity and metabolic syndrome : potential benefit from specific nutritional components / Nutr Metab Cardiovasc Dis 21(Suppl 2):B1~B15
Czekajło A / 2019 / Association between dietary patterns and metabolic syndrome in the selected population of Polish adults-results of the PURE Poland study / Eur J Public Health 29(2):335~340
Meigs JB / 2007 / Impact of insulin resistance on risk of type 2 diabetes and cardiovascular disease in people with metabolic syndrome / Diabetes Care 30(5):1219~1225
Martínez-Augustin O / 2012 / Bioactive anti-obesity food components / Int J Vitam Nutr Res 82(3):148~156
Abete I / 2011 / Obesity and metabolic syndrome : potential benefit from specific nutritional components / Nutr Metab Cardiovasc Dis 21(Suppl 2):B1~B15
Czekajło A / 2019 / Association between dietary patterns and metabolic syndrome in the selected population of Polish adults-results of the PURE Poland study / Eur J Public Health 29(2):335~340
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UCI(KEPA) : I410-ECN-0101-2020-594-001155669