지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 경희한의학연구센터 Oriental pharmacy and experimental medicine Oriental pharmacy and experimental medicine 제4권 제1호
- 발행연도
- 2004.1
- 수록면
- 37 - 43 (7page)
이용수
초록· 키워드
오류제보하기
The effects of Aegle marmelos (Rutaceae) leaf, Emblica officinalis (Euphorbiaceae) fruit and Ocimum sanctum. (Labiateae) leaf extracts were studied in L-thyroxine (0.5 mg/kg) induced hyperthyroidic mice. Separately combined effects of these three plant extracts and of a commonly used antithyroidic drug, Propyl thiouracil (PTU) were investigated for comparison. Serum concentration of thyroxine $(T_4)$, triiodothyronine $(T_3)$, glucose and the activity of hepatic Glucose 6-Phosphatase (G-6-Pase) were considered as main parameters. Hepatic lipid peroxidation (LPO), superoxide dismutase (SOD) and Catalase (CAT) activities were also studied to reveal the toxic effect of the plant extracts, if any. While exogenous $T_4$ enhanced serum concentration of $T_4$, $T_3$, glucose and the activity of hepatic G-6-Pase, a simultaneous administration of either A. marmelos leaf (1.0 mg/kg), E. officinalis fruit( 30 mg/kg) and O. sanctum leaf (50 mg/kg) extracts, to hyperthyroidic animals decreased all these parameters. However, the effects were more pronounced, as nearly normal thyroid function and serum glucose concentration were exhibited when all three plant extracts were administered together. A decrease in LPO and a concomitant increase in SOD and the CAT activities indicated the safe and antiperoxidative nature of the plant extracts, administered either alone or in combination. Our findings reveal that the three test plant materials exhibit synergistic effects without any hepatotoxicity, suggesting their potential use in the amelioration of hyperthyroidism and/ or hyperglycaemia.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Dose dependent effect of benzene extract of Ocimum sanctum leaves on cauda epididymal spermatozoa of albino rats
Oriental pharmacy and experimental medicine
2009 .01
-
갑상선기능항진증(甲狀腺機能亢進症)에 있어서 $T_3RU$ 및 $T_4$에 관(關)한 임상적(臨床的) 연구(硏究)
대한핵의학회지
1978 .01
-
억간산이 갑상선기능항진 유발 백서에 미치는 영향
동의생리병리학회지
2012 .01
-
Snake venom neutralising factor from the root extract of $Emblica$ $officinalis$ $Linn.$
Oriental pharmacy and experimental medicine
2011 .01
-
억간산이 갑상선기능항진 유발 백서에 미치는 영향
동의생리병리학회지
2012 .10
-
Reversible histoarchitecture study of testis and cauda epididymis and changes in cauda epididymal epithelial cell types on treatment with benzene extract of Ocimum sanctum leaves in albino rats
Oriental pharmacy and experimental medicine
2008 .01
-
갑상선기능항진증(甲狀腺機能亢進症)의 임상(臨床) 및 실험적(實驗的) 연구(硏究)
대한핵의학회 학술대회
1966 .01
-
갑상선(甲狀腺) 기능항진증(機能亢進症)에서 $Tapazole^{(R)}$이 $^{131}I$섭취율(攝取率)에 미치는 영향(影響)에 관(關)한 임상적(臨床的) 고찰(考察)
대한핵의학회지
1969 .01
-
Central nervous system depressant effect of hot water extract of Ocimum sanctum Linn. (Labiateae)
Oriental pharmacy and experimental medicine
2002 .01
-
Invitro antifilarial potential of the leaf extract of Oscimum sanctum on cattle filarial parasite Setaria cervi
Oriental pharmacy and experimental medicine
2004 .01
-
갑상선 기능 항진증의 외과적 치료에 대한 임상적 고찰
Annals of Surgical Treatment and Research
1993 .01
-
Diabetes, Glucose Transport and Hypoglycaemic Agents
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2004 .01
-
후박 에탄올 추출물의 불안 및 인지기능에 대한 효과
대한한방내과학회지
2015 .01
-
Inhibitory effects of magnolia officinalis extract on the periodontitis
한국실험동물학회 학술발표대회 논문집
2017 .02
-
Levothyroxine으로 유발된 갑상선기능항진증 랫트에 대한 양격산화탕, 팔물군자탕 및 청폐사간탕의 효능 비교연구
JSCM : Journal of Sasang constitutional medicine
2016 .01
-
하고초추출물의 갑상선기능항진증 랫트모델에서의 한열조절작용에 의한 개선효능 연구
대한본초학회지(본초분과학회지)
2018 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0