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논문 기본 정보

자료유형
학술저널
저자정보
Reezal, I. (Department of Biomedical Science, Faculty of Medicine and Health Sciences) Somchit, MN (Department of Biomedical Science, Faculty of Medicine and Health Sciences) Nur, I. Elysha (Department of Biomedical Science, Faculty of Medicine and Health Sciences) Hasmawie, R. (Department of Biomedical Science, Faculty of Medicine and Health Sciences) Chong, PP (Department of Biomedical Science, Faculty of Medicine and Health Sciences) Mutalib, AR (Department of Pathology and Microbiology, Faculty of Veterinary Medicine, University Putra Malaysia) Ahmad, Z. (Department of Biomedical Science, Faculty of Medicine and Health Sciences)
저널정보
경희한의학연구센터 Oriental pharmacy and experimental medicine Oriental pharmacy and experimental medicine 제3권 제4호
발행연도
2003.1
수록면
191 - 195 (5page)

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Euphorbia hirta, locally called 'ara tanah' or 'susun nabi' in Malaysia is a small annual herb common to the tropical countries and belongs to the same family as the tic and tapioca. E. hirta has had a long history of usage in the treatment of various ailments. In this current study, in vitro sensitivity test of crude aqueous and ethanol extracts of leaves and barks of E. hirta was carried out against bacteria (Escherichia coli, Salmonella enteritidis, Staphylocccus aureus and Bacillus subtilis) and fungi (Microsporum canis, Aspergillus fumigatus, Candida albicans and Candida tropicalis) using the discs diffusion method. The extract-impregnated discs (20, 40 and $80\;{\mu}g/{\mu}l$), the E. hirta extracts inhibited the growth of all the bacteria tested. The growth of C. albicans was inhibited in a concentration dependent manner by the aqueous leaves and barks extracts. C. tropicalis was found to be sensitive to the aqueous leaves extracts. The results were compared to antibacterial drugs of chloramphenicol, ampicilin, penicillin G, and enrofloxacine; and to antifungal drug of ketoconazole, itraconazole and miconazole. In this current study, it can be concluded that this plant has antimicrobial activity that is as potent as the standard antimicrobial drugs against certain microorganisms.

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