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자료유형
학술저널
저자정보
Shin, Hye-Young (Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University) You, Hyeon-Hee (Department of Oral Biochemistry, School of Dentistry, Wonkwang University) Shin, Tae-Yong (College of Phamacy, Woosuk University) Kim, Hyung-Min (Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University) You, Yong-Ouk (Department of Oral Biochemistry, School of Dentistry, Wonkwang University)
저널정보
경희한의학연구센터 Oriental pharmacy and experimental medicine Oriental pharmacy and experimental medicine 제3권 제1호
발행연도
2003.1
수록면
40 - 45 (6page)

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We studied the effect of Bamboo salt-pro on the growth and acid production of S. mutans. The growth of S.mutans was reduced by the presence of the Bamboo salt-pro (1 mg/ml) and NaCl (1 mg/ml) significantly, and the positive control group (1 % of NaF) also exhibited antibacterial activity significantly. Bamboo salt-pro (1 mg/ml) reduced the rate of acid production by S. mutans. Bamboo salt alone did not demonstrate such a reduction in acid production at the concentration of 1 mg/ml. The inhibitory action of Bamboo salt-pro on acid production was found at a concentration of 1 mg/ml, but bamboo salt alone was not at a concentration of 1 mg/ml. In addition, we investigated the anti-inflammatory effect of Bamboo salt-pro on human mast cell line HMC-1. Bamboo salt-pro (0.1 and 0.01 mg/ml) inhibited significantly the secretion of inflammatory cytokine, tumor necrosis factor-a with $59.47{\pm}0.15%$, $51.98{\pm}0.16%$ respectively. Our results suggest that Bamboo salt-pro importantly contributes to the prevention or treatment of periodontitis and other oral diseases and inflammatory diseases.

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