지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 111 - 122 (12page)
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초록· 키워드
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The present study was designed to explore the antioxidant effect of Bamboo powder and its immunor-eactivity in pigs. We investigated the functional properties of Bamboo extracts by means of measuring the contents of total polyphenols and flavonoid as well as determining ABST, DPPH radical scavenging activity, and hydroxyl radical scavenging activity and anticancer activity. The total phenolic compound and flavonoids contents of Bamboo extracts were 171.25 mg/g and 127.5 mg/g, respectively. The DPPH radical, hydroxyl radical, ABST radical scavenging activity of Bamboo extracts were 17.3%, 12.5% and 21.5%, respectively. Evidenced by MTT and cell cycle assay, Bamboo dose-dependently inhibited the cell proliferation and induced G0/G1-phase arrest in CHO cells at concentrations of 100, 250, and 500 µg/ml Bamboo extracts. More than 80% of apoptotic cells were observed by staining with annexin V in 500 µg/ml Bamboo-treated CHO cells, indicating that Bamboo had potent anticancer activities. Next, to investigate the effect of Bamboo on cytokine, immunoglobulin concentration, and blood compositions, flatting pigs were fed with Bamboo powder for 38 days. Flatting pigs were divided into 4 groups; basal diet (control), basal diet supplemented with 1% Bamboo powder (T1), 2% Bamboo powder (T2), and 3% Bamboo powder (T3). The level of hemoglobin increased in the all Bamboo-fed groups compared with the normal control group. In particular, platelet levels in the all Bamboo-treated groups increased by approximately 90% compared with the levels from pig on a normal control. Serum levels of im-munoglobulins (IgG, IgA) in the pigs fed Bamboo powder were modestly increased, and the interferon-γ level also was strongly increased in 2% or 3% Bamboo-fed groups compared with the levels in control groups. Together, these results demonstrated that Bamboo extracts had an effective capacity of scaveng-ing for ABTS, DPPH, and hydroxyl radicals and showed correlation with potent phenol and flavonoid contents, thus suggesting its antioxidant potential. Moreover, administration of Bamboo in 2∼3% im-proved blood parameters and platelets, and especially immunity-related ones such as IgG, IgA, and in-terferon-γ, leading to be potential feed additives in flatting pigs.
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참고문헌 (30)
참고문헌 신청
Ancerewicz J / 1998 / Structure-property relationships of trimetazidine derivatives and model compounds as potential antioxidants / Free Radic Biol Med 25 : 113 ~ 120
Bloknina O / 2003 / Antioxidants, oxidative damage and oxygen deprivation stress / Ann Bot 91 : 179 ~ 194
Bosoi CR / 2013 / Oxidative stress : a systemic factor implicated in the pathogenesis of hepatic encephalopathy / Metab Brain Dis 28 : 175 ~ 178
Brand-Williams W / 1995 / Use of a free radical method to evaluate antioxidant activity. LWT-Food Sci / Technol 28 : 25 ~ 30
Dausch, JG / 1990 / Garlic : A review of its relationship to malignant disease / Preventive Medicine 19 : 346 ~ 361
Bloknina O / 2003 / Antioxidants, oxidative damage and oxygen deprivation stress / Ann Bot 91 : 179 ~ 194
Bosoi CR / 2013 / Oxidative stress : a systemic factor implicated in the pathogenesis of hepatic encephalopathy / Metab Brain Dis 28 : 175 ~ 178
Brand-Williams W / 1995 / Use of a free radical method to evaluate antioxidant activity. LWT-Food Sci / Technol 28 : 25 ~ 30
Dausch, JG / 1990 / Garlic : A review of its relationship to malignant disease / Preventive Medicine 19 : 346 ~ 361
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