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논문 기본 정보

자료유형
학술저널
저자정보
Kim, Young-So (College of Pharmacy, Chungbuk National University) Eo, Seong-Kug (College of Pharmacy, Chungbuk National University) Oh, Ki-Wan (College of Pharmacy, Chungbuk National University) Lee, Chong-Kil (College of Pharmacy, Chungbuk National University) Lee, Young-Nam (College of Natural Sciences, Chungbuk National University) Han, Seong-Sun (College of Pharmacy, Chungbuk National University)
저널정보
한국균학회 Mycobiology Mycobiology 제29권 제1호
발행연도
2001.1
수록면
11 - 14 (4page)

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A preparation of water soluble components(EA) was made from carpophores of Elfvingia applanata(Pers.) Karst and its in vitro antibacterial activity on a number of bacterial species was examined by macrobroth dilution assay. Among 16 species of bacteria tested, the most potent antibacterial activity was observed against Staphylococcus epiderrnidis and Proteus vulgaris, of which MICs were 1.25 mg/ml. To investigate the antibacterial effects in combinations of EA with quinolone antibiotics, such as ciprofloxacin, enoxacin, lomefloxacin, norfloxacin, and ofloxacin, the fractional inhibitory concentrations(FICs) and the fractional inhibitory concentration indices(FICIs) for four bacterial strains were determined by macrobroth dilution checkerboard assay. Combinations of EA and quinolones exhibited either additive or indifferent effects of antibacterial activity in most instances. However, both synergistic and antagonistic effects were not observed in any cases.

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