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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.1
- 수록면
- 1,327 - 1,333 (7page)
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Many traditional herbal remedies exhibit several beneficial effects including anti-inflammation. Panax notoginseng Buck F.H. Chen. is used as a therapeutic agent to stop haemorrhages and a tonic to promote health in Korean and Chinese medicine. The pharrnacokinetic profiles of the main P. notoginseng are still not accurately investigated. The exact mechanism of the anti-inflammatory action of P. notoginseng, however, has not been determined. In the present study, we examined the effect of P. notoginseng on lipopolysaccharide (LPS)-induced nitric oxide (NO) production, and inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) gene expression in RAW264.7 macrophages. The results indicated that P. notoginseng concentration-dependently inhibited LPS-induced NO production. Furthermore, P. notoginseng inhibited the expression of LPS-induced iNOS and COX-2 proteins without an appreciable cytotoxic effect on RAW264.7 cells. Berberine also inhibited LPS-induced iNOS protein as potently as P. notoginseng. This was consistent with the findings that P. notoginseng and also berberine inhibited prostaglandin E2 synthesis induced by LPS.
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Inhibitory effect of Panax notoginseng and emodin on LPS-induced iNOS, COX-2 and prostaglandin E2
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Inhibitory Effect of Panax notoginseng and Berberine on LPS-induced iNOS, COX-2 and Prostaglandin E2
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2006 .10
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Inhibitory effect of Panax notoginseng and berberine on LPS-induced iNOS, COX-2 and prostaglandin E2
대한동의병리학회 학술대회논문집
2006 .09
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Inhibitory effect of Panax notoginseng and emodin on LPS-induced iNOS, COX-2 and prostaglandin E2
동의생리병리학회지
2006 .06
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고콜레스테롤 식이로 유발된 동맥경화병태흰쥐의 혈관조직내 지질과산화 및 산화스트레스에 대한 삼칠근의 영향
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2006 .01
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Inhibitory Effect of Panax notoginseng on Nitric Oxide Synthase, Cyclo-oxygenase-2 and Neutrophil Functions
동의생리병리학회지
2006 .01
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三七花의 대식세포로부터 LPS에 의해 유도되는 nitric oxide와 전염증성 사이토카인의 생성 억제효과
대한한의학회지
2009 .01
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An Influence of Panax notoginseng on the Atherosclerosis Induced by High-cholesterol Feed in Rats
대한동의병리학회 학술대회논문집
2006 .09
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삼칠근(三七根)의 LPS에 의해 활성화된 뇌신경교세포(腦神經膠細胞)로부터의 염증매개물질(炎症媒介物質) 생성억제효과(生成抑制效果)
대한본초학회지(본초분과학회지)
2006 .01
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Investigating chemical features of Panax notoginseng based on integrating HPLC fingerprinting and determination of multiconstituents by single reference standard
Journal of Ginseng Research
2018 .06
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Effect of Panax notoginseng on Hepatic Microvascular Dysfunction in Rats
동의생리병리학회지
2006 .12
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Endophytic fungi harbored in Panax notoginseng : diversity and potential as biological control agents against host plant pathogens of root-rot disease
Journal of Ginseng Research
2017 .07
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Inhibitory Effect of Panax notoginseng on Nitric Oxide Synthase, Cyclo-oxygenase-2 and Neutrophil Functions
동의생리병리학회지
2006 .10
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Inhibitory Effect of Panax notoginseng on Nitric Oxide Synthase, Cyclo-oxygenase-2 and Neutrophil Functions
대한동의병리학회 학술대회논문집
2006 .09
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Rhizospheric fungi of Panax notoginseng: diversity and antagonism to host phytopathogens
Journal of Ginseng Research
2016 .04
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Study on the grading standard of Panax notoginseng seedlings
Journal of Ginseng Research
2018 .04
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New dammarane-type triterpenoids from the leaves of Panax notoginseng and their protein tyrosine phosphatase 1B inhibitory activity
Journal of Ginseng Research
2014 .01
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Diversity, distribution, and antagonistic activities of rhizobacteria of Panax notoginseng
Journal of Ginseng Research
2016 .04
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황련(黃連)의 주성분인 Berberine의 뇌신경소교세포로부터 LPS에 의해 유도되는 염증매개물질 생성억제효과
대한본초학회지(본초분과학회지)
2007 .01
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