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논문 기본 정보

자료유형
학술저널
저자정보
Jun, Jae-Yeoul (Department of Physiology, Chosun University College of Medicine) Yeum, Cheol-Ho (Department of Physiology, Chosun University College of Medicine) Goo, Yong-Sook (Department of Physiology, Chungbuk National University, College of Medicine) Kim, Jun (Department of Physiology, Seoul National University College of Medicine)
저널정보
대한생리학회 대한생리학회지 대한생리학회지 제25권 제2호
발행연도
1991.1
수록면
201 - 209 (9page)

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The rostral ventrolateral medulla (RVLM) has been established recently as a sympathoexcitatory area. The present study was conducted to investigate whether the somatosympathetic pressor and/or depressor responses are mediated through RVLM in cats anesthetized with ${\alpha}-chloralose$. An occipital craniectomy was performed and ventrolateral medulla were stimulated either electrically or chemically to evoke changes in arterial blood pressure. And then the effect of lesions in the ventrolateral medulla on the changes in blood pressure elicited by the peripheral nerve stimulation was observed. Followings are the results obtained: 1) Pressor areas were found in the ventrolateral medulla, lateral reticular nucleus and rostral dorsal area. 2) Depressor areas were found mainly in the ventrolateral medulla rostral to the pressor areas. 3) Some areas showed biphasic responses: a depressor response to lower frequency and a pressor response to higher frequency stimulation. 4) After electrical lesion in pressor area in RVLM, the somatosympathetic pressor response was abolished or depressed markedly. The somatosympathetic depressor response, however, remained after the lesion. 5) Electrical lesion in the depressor area abolished somatosympathetic depressor response. From the above results it is concluded that somatosympathetic pressor response is mediated through RVLM, while somatosympathetic depressor response is not mediated through RVLM.

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