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논문 기본 정보

자료유형
학술저널
저자정보
Huh, Min-Gang (Department of Physiology & Biophysics, Seoul National University, College of Medicine) Yan, Hai-Dun (Department of Physiology & Biophysics, Seoul National University, College of Medicine) Lim, Won-Il (Department of Physiology & Biophysics, Seoul National University, College of Medicine) Kim, Jun (Department of Physiology & Biophysics, Seoul National University, College of Medicine)
저널정보
대한생리학회 대한생리학회지 대한생리학회지 제29권 제2호
발행연도
1995.1
수록면
309 - 321 (13page)

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In the present study, the relationship between the somatosympathetic reflexes and arterial blood pressure responses to electrical stimulation of the peripheral nerve was investigated in cats anesthetized with ${\alpha}-chloralose$. Single sympathetic postganglionic fiber activities were recorded from the hindlimb muscle and skin nerves and also from the cervical and abdominal sympathetic chains. Effects of the morphine on responses of the sympathetic nerve and arterial blood pressure to activation of the peripheral $A{\delta}-$ and C-afferent nerves were analyzed. The following results were obtained. 1) Arterial blood pressure was depressed by peripheral AS-afferent stimulation (A-response) and was elevated during C-afferent activation (C-response). 2) Intravenously administered morphine enhanced the C-response while the A-response decreased insignificantly, Only the C-response was decreased by intrathecal morphine. 3) All the ten recorded cutaneous sympathetic fibers showed periodic discharge pattern similar to respiratory rhythm and five of them also showed cardiac-related rhythm. However, most of the muscular sympathetic fibers had cardiac-related rhythm and only four fibers showed respiratory rhythm. 4) Morphine decreased the sympathetic C-reflex elicited by the peripheral C-afferent activation and the abdominal sympathetic A-reflex was also decreased by morphine. From the above results, it was concluded that supraspinal mechanisms were involved in the enhanced arterial pressor response to peripheral C-afferent activation by intravenous morphine.

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