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논문 기본 정보

자료유형
학술저널
저자정보
한준구 (국군서울지구병원 방사선과)
저널정보
대한영상의학회 대한방사선의학회지 대한방사선의학회지 제24권 제6호
발행연도
1988.1
수록면
933 - 941 (9page)

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Abdominal aortography and histopathologic examination after absolute ethanol infusion ar fast (0.4cc/sec) and slow speed(0.04cc/sec) were performed on 16 rats(2 controls. 7 fast infusion group. 7 slow infusion group) Angiographic and histopathologic findings were correlated and the findings of slow and fast infusion groups were studied. the results are as follows; 1. Histopathologic findings of the fast infusion group revealed wide area of glomerular and tubular collapes obliteration of the free space between the Bowmann's capsule and glomerulus sloughing and loss of the endothelium fresh thrombi attached to the wall and cleavage of the muscle layer of the arteries. 2. Angiographic findings of the fast infusion group revealed luminal irregularity early obstruction of the aorta and the renal arteries and delayed circulation time. 3. Histopathologic findings of the slow infusion group revealed degenerated coalesced red blood cell packed in the glomeruli focal areas of severe glomerular and tubular damage on relatively normal background en-dothelial and muscular damage of the arteries. 4. Angiographic findings of the slow infusion group revealed focal perfusion defect of the kidney delayed cir-culation time and mild luminal irregularity but there was no obstruction of the major arteries. 5. In conclusion author believes that endothelial damage and thrombus formation from the damaged vessel wall as well as direct cytotoxicity and in situ emboli formation play a significant role in the embolic effect of absolute ethanol.

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