방역작업자의 브롬화메틸(methyl bromide) 노출수준과 생물학적 모니터링

이종성; 이용학; 신재훈; 최정근; 오차재; 정호근

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자료유형: 학술저널

저자정보: 이종성 (한국산업안전공단 산업안전보건연구원) 이용학 (한국산업안전공단 산업안전보건연구원) 신재훈 (한국산업안전공단 산업안전보건연구원) 최정근 (한국산업안전공단 산업안전보건연구원) 오차재 (부산대학교 의과대학 예방의학교실) 정호근 (한국산업안전공단 산업안전보건연구원)

저널정보: 한국산업보건학회 (구 한국산업위생학회) 한국산업보건학회지 한국산업보건학회지 제11권 제3호

발행연도: 2001.1

수록면: 212 - 218 (7page)

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This study was performed to estimate environmental and biological monitoring of workers exposed to methyl bromide through quarantine fumigation. Airborne methyl bromide and it's metabolites were analyzed by gas chromatography and ion chromatography, respectively. The results are as followings; airborne concentration of methyl bromide(TWA) was $2.08{\pm}1.56ppm$(N=8). Dispersion and setting/degas groups were $0.67{\pm}0.12ppm$(N=2) and $2.54{\pm}1.53ppm$(N=6), respectively. Bromide ion concentration in serum was $23.40{\pm}14.91mg/{\ell}$(N=10) in the exposed workers and $4.74{\pm}0.82mg/{\ell}$(N=21) in the non-exposed workers. Bromide ion concentration in urine was $35.56{\pm}26.89mg/{\ell}$(N=11) in exposed group and $6.62{\pm}2.31mg/{\ell}$(N=21) in non-exposed group. Good correlation was observed between concentration of serum and urine ($r^2$=0.890 p<0.01). No significant correlations of other determinants were observed. Calculated from a regressive curve, the biological half lifes of serum and urine were 10.7 and 5.9 days. In these results, biological monitoring of bromide ion of serum and urine provided useful information for evaluating exposure of workers to methyl bromide, so that an availability of bromide ion of biological samples was showed as biological monitoring indices for methyl bromide.

#Methyl bromide #Bromide ion #Bromomethane #Quarantine fumigator #Biological monitoring

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소속기관 근로복지공단 직업환경연구원

주요연구분야 의약학 > 기초의학 > 예방의학·직업환경의학 의약학 > 임상의학 > 내과학

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