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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology 제8권 제3호
- 발행연도
- 2000.1
- 수록면
- 235 - 240 (6page)
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초록· 키워드
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Antitumor effect of LC43, a protein-bound ploysaccharide (M.W. 43 kDa) that was purified from intergeneric protoplast fusant of Lentinus edodes and Coriolus versicolor, was elucidated against mouse sarcoma 180 cell in vitro and in vivo. By injecting LC43 into ICR mice bearing solid or ascitic sarcoma 180, tumor regression and survival rates were investigated. To examine the effects of LC43 on immunopotentiation activity. immunoorgan weight, B cell differentiation, T cell activity and macrophage activation were determined. LC43 showed antitumor effects against both solid tumor and ascitic tumor of sarcoma 180. It did not change significantly the immunoorgan weight but potentiated immune responses such as B cell differentiation and the release of superoxide anion from macrophages. These results suggest that the protein-bound polysaccharide of LC43 exhibited antitumor activities through the activation of immune-related cells and acted as an immunmodulator.
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영지와 표고의 융합체의 면역활성 증강작용
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2000 .01
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Studies on the Constituents of Higher Fungi of Korea (XXIII)
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1979 .01
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복수형 Sarcoma 180 종양세포의 시험관내 계대배양
JOURNAL OF BACTERIOLOGY AND VIROLOGY
1990 .06
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Characteristics of Artificial Hybrids between Lentinula edodes and Coriolus versicolor
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1997 .01
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Studies on Intergeneric Protoplast Fusion and Nuclear Transfer between Ganoderma Incidum and Coriolus versicolor
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1991 .01
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