지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 1996.1
- 수록면
- 211 - 211 (1page)
이용수
초록· 키워드
오류제보하기
Changes in glutamate release and uptake on cerebellar cells after the chronic exposure to lead were investigated. Rats were received 0.25% lead acetate in drinking water from the beginning of the pregnancy. The control group was given 0.125% sodium acetate in drinking water. The cerebellar cells from 7 or 8 day-old pups were cultured. Amino acid release from cerebellar granule cells and the glutamate uptake into cerebellar glial cells were measured using HPLC-ECD. Basal glutamate release and NMDA-induced glutamate release didn't show significant difference. However, the other amino acids in the granule cells obtained from lead exposed pups were less released than the control after the stimulation by NMDA (50$\mu$M). SNAP-induced (50$\mu$M) glutamate release was significantly reduced in granule cells prepared from lead exposed pups. The basal glutamate uptake in glial cells didn't show any difference. However, the uptake in glial cells prepared from lead exposed pups was significantly less blocked by PDC (24$\mu$M) compared to the control group. These results indicate that lead exposure to the mother might affect the Excitatory amino acid system during the development of the offspring.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Effects of Chronic Lead Exposure on Glutamate Release and Uptake in Cerebellar Cells of Rat Pups
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1998 .01
-
Effects of dehydroevodiamine on the release and uptake of glutamate in cultured cerebellar cells
대한약학회 학술대회
2000 .01
-
Subacute Nicotine Exposure in Cultured Cerebellar Cells Increased the Release and Uptake of Glutamate
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2000 .01
-
Inhibitory Effect of Fangchinoline on Excitatory Amino Acids. Induced Neurotoxicity in Cultured Rat Cerebellar Granule Cells
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2001 .01
-
Chronic exposure of nicotine modulate the expressions of cerebellar glial glutamate transporters in rats
대한약학회 학술대회
2002 .01
-
High glucose stimulates glutamate uptakes in pancreatic β-cells
Laboratory Animal Research
2011 .12
-
소풍탕이 Glutamate에 의한 C6 Glial Cell의 Apoptosis에 미치는 영향
동의생리병리학회지
2008 .12
-
장기간 납의 투여에 따른 뇌 glutamate 신경계 변화에 대한 연구
Toxicological Research
1999 .06
-
歸脾湯이 Glutamate에 의한 C6 glial Cell의 Apoptosis에 미치는 영향
대한한의학회지
2001 .12
-
Glutamate 로 유도된 C6 glial 세포의 독성에 대한 八物湯의 보호 효과
동의생리병리학회지
2012 .08
-
Nicotine alters the characteristics of cAMP-exposed cerebellar glial cells
대한약학회 학술대회
2000 .01
-
Effects of Ginsenosides on the Glutamate Release and Intracellular Calcium Levels in Cultured Rat Cerabeller Neuronal Cells
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1995 .01
-
Protective Effect of Fangchinoline on Cyanide-Induced Neuro-toxicity in Cultured Rat Cerebellar Granule Cells
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2002 .01
-
Glutamate에 의한 세포내 칼슘농도변화와 세포독성과의 관계
Toxicological Research
2002 .12
-
Glutamate로 유도된 C6 glial 세포의 독성에 대한 팔물탕(八物湯)의 보호 효과
동의생리병리학회지
2012 .01
-
Protective Effects of Ginsenosides on Cyanide-induced Neurotoxicity in Cultured Rat Cerebellar Granule Cells
Journal of Ginseng Research
2000 .12
-
Effects of betaine on the glutamate-induced neurotoxicity in primary cultured chicken brain cells
한국응용약물학회 신약개발 연구발표회
1993 .01
-
Hypothetical Mechanisms of G protein-coupled neurodegeneration in glutamate excitotoxicity in human SH-SY5Y neuroblastoma cells
대한약학회 학술대회
2003 .01
-
뇌신경 재활의학에서의 소뇌의 비침습적 경두개 자극술의 적용
뇌신경재활
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0