지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 1995.1
- 수록면
- 135 - 136 (2page)
이용수
초록· 키워드
오류제보하기
Resent advances in computer technology have introduced a sophisticated capability for computing the biological fate of toxicants in a biological system. This methodology, which has drastically altered risk assessment skill in toxicology, is designed using all the mechanistic information, and all claim better accuracy with extrapolating capability Iron animal to people than conventional pharmacokinetic methods. Biologically based mathematical models in which the specific mechanistic steps governing tissue disposition(pharmacokinetics) and toxic action (pharmacodynamics) of chemicals are constructed in quantitative terms by a set of equations loading to prediction of the outcome of specific toxicological experiments by computer simulation. pharmacokinetic and pharmacodynamic models are useful in risk assessment because their mechanistic biological basis permits the high-to-low dose, route to route and interspecies extrapolation of the tissue disposition and toxic action of chemicals.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Pharmacokinetics and Pharmacodynamic Consideration of Antimicrobial Use
대한약학회 학술대회
2000 .01
-
Pharmacokinetic and Pharmacodynamic Analysis of CNS Drugs
대한약학회 학술대회
2005 .01
-
Development of physiological pharmacokinetic model
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1987 .01
-
Pharmacokinetic and Pharmacodynamic Profiles of BR-A657 in Patients with Essential Hypertension
대한임상약리학회 학술대회
2006 .01
-
The Use of 3-dimensional Cultures for Pharmacokinetic and Pharmacodynamic Study Of Anticancer Agents
대한약학회 학술대회
2004 .01
-
Pharmacokinetic-Pharmacodynamic Modeling for the Relationship between Glucose-Lowering Effect and Plasma Concentration of Metformin in Volunteers
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
-
약동학 및 약력학
대한외과학회 학술대회 초록집
2012 .11
-
Pharmacokinetic-Pharmacodynamic Relationships Under Non-controlled Conditions. Disease-Drug Interactions
한국응용약물학회 추계학술발표논문집
2002 .01
-
항생제 Fluoroquinolones의 약동학 및 약력학에 관한 최신 정보
Urogenital Tract Infection
2015 .01
-
생리학 기반 약물동태(PBPK, Physiologically Based Pharmacokinetic) 모델링을 이용한 소아 약물 동태 예측 연구
약학회지
2015 .01
-
Collaborative Pharmacokinetic–Pharmacodynamic Research for Optimization of Antimicrobial Therapy
Infection and Chemotherapy
2016 .01
-
Intergration of Pharmacokinetics and Pharmacodynamics in Early Phase Clinical Evaluations
대한임상약리학회 심포지움
1993 .01
-
생물학적 모니터링 데이터를 기초한 PBPK 모델의 활용
Environmental Analysis Health and Toxicology
2007 .03
-
Children's Risk Assessments : Pharmacokinetic and Metabolic Bases for Potential Toxic Effects of Chemicals in Infants & Children
환경독성보건학회 심포지엄 및 학술대회
2009 .11
-
Antiplatelet Effect of Low Dose Aspirin: Pharmacokinetic/Pharmacodynamic Analysis
대한임상약리학회 학술대회
1996 .01
-
Clinical Significance of Pharmacokinetic Evaluation
대한임상약리학회 심포지움
1993 .01
-
Pharmacokinetic and Pharmacodynamic Characteristics of Ibandronate in Healthy Subjects
대한임상약리학회 학술대회
2006 .01
-
Pharmacokinetic Assessment in Early Phase Clinical Trials : Design and Data Analysis
대한임상약리학회 심포지움
1993 .01
-
High Performance Liquid Chromatographic Analysis of Rabeprazole in Human Plasma and its Pharmacokinetic Application
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2008 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0