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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2003.1
- 수록면
- 21 - 21 (1page)
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The role of a postsynaptic rise of [C $a^{2+}$]$_{i}$ in the induction of LTP and LTD has been well established. Both the levels and the duration of elevated [C $a^{2+}$]$_{i}$ are important in synaptic plasticity. LTP and LTD could be selectively induced according to intracellular $Ca^{2+}$ concentration. Although the specificity of $Ca^{2+}$ signaling can be achieved not only by amplitude but also by the frequency and duration of the calcium transient, the effects of changing amplitudes of $Ca^{2+}$ transients on synaptic plasticity have been extensively documented, but not so the effects of temporal changes.changes..
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