지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 42 - 49 (8page)
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초록· 키워드
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Purpose: To compare the efficacy of inflammatory markers, the Laboratory-score, and a new laboratory combined model for predicting serious bacterial infection (SBI) in young febrile children. Methods: The presence of SBI was reviewed in previously healthy children aged 3 years or younger with fever (> 38。C) who visited the emergency department from 2017 through 2018. Areas under the curves (AUCs) of the receiver operating characteristic curve for SBI were compared with individual inflammatory markers (white blood cells [WBC] count, erythrocyte sedimentation rate [ESR], C-reactive protein [CRP], procalcitonin [PCT], and urine WBC count), the Laboratory-score, and a laboratory combined model. The latter model was developed using logistic regression analysis including ESR, CRP, and PCT. Results: Of the 203 enrolled children, SBI was diagnosed in 58 (28.6%). For SBI prediction, the Laboratory-score showed 51.7% sensitivity (95% confidence interval [CI], 38.2%-65.0%) and 83.5% specificity (95% CI, 76.4%-89.1%). The AUC of the Laboratory-score (0.76) was significantly superior to the values of all individual inflammatory markers (WBC, 0.59 [P = 0.032]; ESR, 0.69; and CRP, 0.74 [P < 0.001]) except that of PCT (0.77, [P < 0.001]). The AUC of the laboratory combined model (0.80) was superior to that of the Laboratory-score (0.76) (P < 0.001). Conclusion: In this study, the new laboratory combined model showed good predictability for SBI. This finding suggests the usefulness of combining ESR, CRP, and PCT in predicting SBI.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Craig JC / 2010 / The accuracy of clinical symptoms and signs for the diagnosis of serious bacterial infection in young febrile children: prospective cohort study of 15 781febrile illnesses / BMJ 340:c1594
Saxena S / 2009 / Increasing shortstay unplanned hospital admissions among children in England;time trends analysis ‘97-’06 / PLoS One 4:e7484
Lacour AG / 2008 / A score identifying serious bacterial infections in children with fever without source / Pediatr Infect Dis J 27:654~656
Gomez B / 2016 / Validation of the “Step-by-Step” approach in the management of young febrile infants / Pediatrics 138:e20154381
Park JS / 2017 / Retrospective validation of the Step-by-Step approach for febrile infants younger than 90 days in the emergency department / Pediatr Emerg Med J 4:67~74
Saxena S / 2009 / Increasing shortstay unplanned hospital admissions among children in England;time trends analysis ‘97-’06 / PLoS One 4:e7484
Lacour AG / 2008 / A score identifying serious bacterial infections in children with fever without source / Pediatr Infect Dis J 27:654~656
Gomez B / 2016 / Validation of the “Step-by-Step” approach in the management of young febrile infants / Pediatrics 138:e20154381
Park JS / 2017 / Retrospective validation of the Step-by-Step approach for febrile infants younger than 90 days in the emergency department / Pediatr Emerg Med J 4:67~74
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