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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 154 - 161 (8page)
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Background: It is crucial to understand the current status of clinical laboratory practices for the largest outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infections in the Republic of Korea to be well prepared for future emerging infectious diseases.
Methods: We conducted a survey of 49 clinical laboratories in medical institutions and referral medical laboratories. A short questionnaire to survey clinical laboratory practices relating to MERS-CoV diagnostic testing was sent by email to the directors and clinical pathologists in charge of the clinical laboratories performing MERS-CoV testing. The survey focused on testing volume, reporting of results, resources, and laboratory safety.
Results: A total of 40 clinical laboratories responded to the survey. A total of 27,009 MERS-CoV real-time reverse transcription PCR (rRT-PCR) tests were performed. Most of the specimens were sputum (73.5%). The median turnaround time (TAT) was 5.29 hr (first and third quartile, 4.11 and 7.48 hr) in 26 medical institutions. The median TAT of more than a half of the laboratories (57.7%) was less than 6 hr. Many laboratories were able to perform tests throughout the whole week. Laboratory biosafety preparedness included class II biosafety cabinets (100%); separated pre-PCR, PCR, and post-PCR rooms (88.6%); negative pressure pretreatment rooms (48.6%); and negative pressure sputum collection rooms (20.0%).
Conclusions: Clinical laboratories were able to quickly expand their diagnostic capacity in response to the 2015 MERS-CoV outbreak. Our results show that clinical laboratories play an important role in the maintenance and enhancement of laboratory response in preparation for future emerging infections.
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참고문헌 (12)
참고문헌 신청
Cowling BJ / 2015 / Preliminary epidemiological assessment of MERS-CoV outbreak in South Korea, May to June 2015 / Euro Surveill 20:7~13
Hayden RT / 2010 / A survey-based assessment of United States clinical laboratory response to the 2009 H1N1 influenza outbreak / Arch Pathol Lab Med 134:1671~1678
Sullivan SJ / 2010 / 2009 H1N1 influenza / Mayo Clin Proc 85:64~76
Crawford JM / 2010 / Laboratory surge response to pandemic (H1N1) 2009 outbreak, New York City metropolitan area, USA / Emerg Infect Dis 16:8~13
Lautenbach E / 2010 / Initial response of health care institutions to emergence of H1N1 influenza: experiences, obstacles, and perceived future needs / Clin Infect Dis 50:523~527
Hayden RT / 2010 / A survey-based assessment of United States clinical laboratory response to the 2009 H1N1 influenza outbreak / Arch Pathol Lab Med 134:1671~1678
Sullivan SJ / 2010 / 2009 H1N1 influenza / Mayo Clin Proc 85:64~76
Crawford JM / 2010 / Laboratory surge response to pandemic (H1N1) 2009 outbreak, New York City metropolitan area, USA / Emerg Infect Dis 16:8~13
Lautenbach E / 2010 / Initial response of health care institutions to emergence of H1N1 influenza: experiences, obstacles, and perceived future needs / Clin Infect Dis 50:523~527
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