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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 969 - 975 (7page)
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초록· 키워드
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Purpose: Studies on the incidence and mortality of refractures after primary osteoporotic fracture are limited by the relatively rareincidence of such refractures and small sample sizes. The objectives of this research were: 1) to determine the incidence of osteoporoticrefractures and fracture locations and 2) to assess mortality rates associated with osteoporotic refracture over a medianfollow up of 3 years using nationwide claim database. Materials and Methods: Patients over 50 years of age who had an osteoporotic fracture that was confirmed operationally wereenrolled. Refracture was defined as that after 6 months of an untreated period. Mortality rate was calculated using the Charlsoncomorbidity index and was analyzed using Cox proportional hazards regression analysis. Results: A total of 18956 first-time instances of osteoporotic fracture were reported between 2007 and 2012 after a median followup of 3.1 years (range, 1 to 7 years). Among 18956 patients, 2941 (15.50%) experienced refracture. After follow up for 1 year, cumulativemortality rates for re-fracture and non-refracture groups were 9.1% and 7.2%, respectively. After adjusting for covriates,mortality rate was 1.2 times greater in patients with re-fracture than in patients without re-fracture over a median follow up of 3years (hazard ratio: 1.20, 95% confidence interval: 1.08–1.34, p<0.001). Conclusion: The incidence of osteoporotic re-fracture in this nationwide study was 15.5%, and the mortality rate of re-fracturepatients was 1.2 times higher than that of non-refracture patients over a median follow up of 3 years.
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참고문헌 (36)
참고문헌 신청
Lems WF / 2017 / Critical issues and current challenges in osteoporosis and fracture prevention. An overview of unmet needs / Ther Adv Musculoskelet Dis 9:299~316
Kontis V / 2017 / Future life expectancy in 35 industrialised countries : projections with a Bayesian model ensemble / Lancet 389:1323~1335
Doherty DA / 2001 / Lifetime and five-year age-specific risks of first and subsequent osteoporotic fractures in postmenopausal women / Osteoporos Int 12:16~23
Dennison E / 2006 / Epidemiology of osteoporosis / Rheum Dis Clin North Am 32:617~629
이영균 / 2017 / Trend in the Age-Adjusted Incidence of Hip Fractures in South Korea: Systematic Review / Clinics in Orthopedic Surgery 9(4):420~423
Kontis V / 2017 / Future life expectancy in 35 industrialised countries : projections with a Bayesian model ensemble / Lancet 389:1323~1335
Doherty DA / 2001 / Lifetime and five-year age-specific risks of first and subsequent osteoporotic fractures in postmenopausal women / Osteoporos Int 12:16~23
Dennison E / 2006 / Epidemiology of osteoporosis / Rheum Dis Clin North Am 32:617~629
이영균 / 2017 / Trend in the Age-Adjusted Incidence of Hip Fractures in South Korea: Systematic Review / Clinics in Orthopedic Surgery 9(4):420~423
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