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Blood pressure and heart failure
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Type
Academic journal
Author
Journal
대한고혈압학회 Clinical Hypertension Clinical Hypertension 제26권 제2호 KCI Candidated Journals
Published
2020.1
Pages
8 - 15 (8page)

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Blood pressure and heart failure
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Abstract Background: Hypertension is a leading cause of cardiovascular disease, stroke, and death. It affects a substantial proportion of the population worldwide, and remains underdiagnosed and undertreated. Body: Long-standing high blood pressure leads to left ventricular hypertrophy and diastolic dysfunction that cause an increase in myocardial rigidity, which renders the myocardium less compliant to changes in the preload, afterload, and sympathetic tone. Adequate blood pressure control must be achieved in patients with hypertension to prevent progression to overt heart failure. Controlling blood pressure is also important in patients with established heart failure, especially among those with preserved ejection fractions. However, aggressive blood pressure lowering can cause adverse outcomes, because a reverse J-curve association may exist between the blood pressure and the outcomes of patients with heart failure. Little robust evidence exists regarding the optimal blood pressure target for patients with heart failure, but a value near 130/80 mmHg seems to be adequate according to the current guidelines. Conclusion: Prospective studies are required to further investigate the optimal blood pressure target for patients with heart failure

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References (71)

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WHO / World Health Organization Global Health Observatory (GHO) data google schola Levy D / 1996 / The progression from hypertension to congestive heart failure / JAMA 275:1557~1562 google schola Kannel WB / 1998 / Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation : population-based estimates / Am J Cardiol 82:2N~9N google schola McLenachan JM / 1987 / Ventricular arrhythmias in patients with hypertensive left ventricular hypertrophy / N Engl J Med 317:787~792 google schola Vasan RS / 2001 / Impact of high-normal blood pressure on the risk of cardiovascular disease / N Engl J Med 345:1291~1297 google schola

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