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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 245 - 251 (7page)
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초록· 키워드
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Multicellular spheroids (MCSs) from three dimensional culture, which is a complex architecturalstructure with dynamic cell to cell and cell to matrix interactions, mimic real tissues regardingstructural and functional properties. MCSs have emerged as an effective tool for fillingup the gap between the in vitro and in vivo experimental model and can replace the in vivomodel. The viability and functional performance can be enhanced when cells are grown as multicellularspheroid (MCS). In this review paper, we discussed the basic mechanism of MCSformation, their biomedical applications, and recent advances in MCS culture and tissue engineering.
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