지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
The cerebellum is a region of the brain that plays an important role in motor control. It is classified phylogenetically into archicerebellum, paleocerebellum and neocerebellum. The Purkinje cells are lined in a row called Purkinje cell layer and it has a unique dendritic branches with many spines. The previous study reported that there is a difference of synapse density according to the lobules based on large two-dimensional data. However, recent study with high voltage electron microscopy showed there was no differences in dendritic spine density of the Purkinje cell according to its phylogenetic lobule. We analyzed Purkinje cell density in the II, VI and X lobules by stereological modules and synaptic density was estimated by double disector based on Purkinje cell density in the molecular layer of each lobule. The results showed that there was significant difference in the Purkinje cell density and synapse number according to their phylogenetic lobules. The number of Purkinje cell in a given volume was larger in the archicerebellum, but synapse density was higher in the neocerebellum. These data suggest that cellular and synaptic organization of the Purkinje cell is different according to their phylogenetic background.
목차
등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
V. Braitenberg / 1958 / Morphological observations on the cerebellar cortex / J. Comp. Neurol 109:1~33
C. A. Fox / 1957 / A quantitative study of the Purkinje cell dendritic branchlets and their relationship to afferent fibres / J. Anat 91:299~313
P. F. Gilbert / 1977 / Purkinje cell activity during motor learning / Brain Res 128:309~328
H. J. Gundersen / 1988 / The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis / APMIS 96:857~881
H. Heinsen / 1983 / Quantitative studies on regional differences in Purkinje cell dendritic spines and parallel fiber synaptic density / Anat. Embryol 168:361~370
C. A. Fox / 1957 / A quantitative study of the Purkinje cell dendritic branchlets and their relationship to afferent fibres / J. Anat 91:299~313
P. F. Gilbert / 1977 / Purkinje cell activity during motor learning / Brain Res 128:309~328
H. J. Gundersen / 1988 / The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis / APMIS 96:857~881
H. Heinsen / 1983 / Quantitative studies on regional differences in Purkinje cell dendritic spines and parallel fiber synaptic density / Anat. Embryol 168:361~370
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