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This study was conducted to evaluate the functionality of fermented black garlic extracts under various conditions. Black garlic powder was prepared by aging for 0~72 hours at 80℃ depending on relative humidity (RH). It showed the highest antioxidant effects among the samples; the total antioxidant activity of black garlic powders at RH 75%, 84%, and 90% for 72 hours was increased 31.9 times, 28.2 times, and 22.6 times compared with that of the fresh garlic powder, respectively. Also, the alliin content was gradually decreased. S-ally-L-cysteine and S-ethyl-cysteine levels were increased; the highest values were 495.9 μg/g and 1,769.7 μg/g after aging for 72 hours at RH 75%. Aspartate transaminase (AST) and alanine transaminase (ALT) levels were increased following high fat diet feeding, but the rise was obviously reduced by administration of black garlic extract. The total cholesterol, LDL/VLDL-cholesterol, and triglyceride contents in serum were significantly lower in methionine and choline deficient (MCD) diet treatment groups than in the positive control group. The concentration was increased following the intake of black garlic and fermented black garlic extracts. Therefore, black garlic extracts could be an ideal material as a dietary supplement in healthy functional foods to improve the effects on fatty liver. Key words: fermented black garlic extract, anti-obesity, hepatoprotection, antioxidant activity, S-allyl-L-cysteine
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참고문헌 (38)
참고문헌 신청
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AOAC / 1955 / Official Method of Analysis. 8th ed / Association of Official Agricultural Chemists :144
Argo CK / 2009 / Epidemiology and natural history of non-alcoholic steatohepatitis / Clin Liver Dis 13:511~531
Benzie IF / 1996 / The ferric reducing ability of plasma(FRAP)as a measure of"antioxidant power" : The FRAP assay / Anal Biochem 239:70~76
Anstee QM / 2013 / Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis / Nat Rev Gastroenterol Hepatol 10:330~344
AOAC / 1955 / Official Method of Analysis. 8th ed / Association of Official Agricultural Chemists :144
Argo CK / 2009 / Epidemiology and natural history of non-alcoholic steatohepatitis / Clin Liver Dis 13:511~531
Benzie IF / 1996 / The ferric reducing ability of plasma(FRAP)as a measure of"antioxidant power" : The FRAP assay / Anal Biochem 239:70~76
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