지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 169 - 173 (5page)
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초록· 키워드
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The GENEDIA MTB/NTM Detection Kit (GENEDIA MTB/NTM; Green Cross Medical Science Corp., Chungbuk, Korea) is a multiplex real-time PCR assay used for differential identification of Mycobacterium tuberculosis complex (MTBC) and nontuberculous mycobacteria (NTM). While the importance of differential identification of MTB/NTM is recognized, there is limited data on the performance of GENEDIA MTB/NTM assay to date. A total of 687 consecutive sputum specimens were cultured and analyzed with the GENEDIA MTB/NTM and GENEDIA MTB assays. Nineteen specimens (2.8%) were MTBC-positive, and 69 (10.0%) were NTM-positive based on mycobacterial culture. All specimens showed concordant results for MTBC using both assays, with a kappa value of 1.00, overall sensitivity of 63.2% (12/19), and specificity of 100% (668/668). The overall NTM sensitivity and specificity were 23.2% (16/69) and 99.7% (616/618) for GENEDIA MTB/NTM. The association between NTM-positivity using GENEDIA MTB/NTM and the diagnosis of NTM pulmonary disease was not statistically significant. In conclusion, the two real-time PCR assays showed similar diagnostic performance for MTBC detection. However, the sensitivity for NTM detection was lower than that for MTBC detection.
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등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
World Health Organization / Global tuberculosis report 2018
Honda JR / 2018 / Global environmental nontuberculous mycobacteria and their contemporaneous man-made and natural niches / Front Microbiol 9:2029
전두수 / 2019 / Infection Source and Epidemiology of Nontuberculous Mycobacterial Lung Disease / Tuberculosis and Respiratory Diseases 82(2):94~101
Lee H / 2019 / Epidemiology of nontuberculous mycobacterial infection, South Korea, 2007-2016 / Emerg Infect Dis 25:569~572
류연주 / 2016 / Diagnosis and Treatment of Nontuberculous Mycobacterial Lung Disease: Clinicians’ Perspectives / Tuberculosis and Respiratory Diseases 79(2):74~84
Honda JR / 2018 / Global environmental nontuberculous mycobacteria and their contemporaneous man-made and natural niches / Front Microbiol 9:2029
전두수 / 2019 / Infection Source and Epidemiology of Nontuberculous Mycobacterial Lung Disease / Tuberculosis and Respiratory Diseases 82(2):94~101
Lee H / 2019 / Epidemiology of nontuberculous mycobacterial infection, South Korea, 2007-2016 / Emerg Infect Dis 25:569~572
류연주 / 2016 / Diagnosis and Treatment of Nontuberculous Mycobacterial Lung Disease: Clinicians’ Perspectives / Tuberculosis and Respiratory Diseases 79(2):74~84
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