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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 196 - 205 (10page)
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초록· 키워드
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Background/Aims: The purpose of this study was to investigate the risk factors and long-term clinical outcomes of non-curativeresection (NCR) in a large-scale patient population. Methods: We retrospectively analyzed the clinical data of 3,094 patients who underwent endoscopic submucosal dissection (ESD) ofearly gastric cancer from March 2005 to March 2018 at 13 institutions in Korea. We analyzed the risk factors for NCR and the survivalbetween patients with curative resection and those with NCR with no additional treatment. Results: The NCR rate was 21.4% (661/3,094). In multivariate regression analysis, the risk factors affecting NCR with ESD were oldage, undifferentiated tumor, tumor location in the upper body, tumor size ≥2 cm, and presence of an ulcer. In Cox proportional hazardregression analysis, tumor size ≥2 cm, submucosal invasion, positive horizontal margin, and lymphovascular invasion were risk factorsfor local recurrence. In Kaplan-Meier analysis, there was no statistically significant difference in the overall survival between the twogroups (log-rank p=0.788). However, disease-specific survival was significantly lower in the NCR group (log-rank p=0.038). Conclusions: Clinicians should be aware of the risk factors for NCR and local recurrence after ESD for early gastric cancer, and shouldconsider providing additional treatment after NCR.
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참고문헌 (29)
참고문헌 신청
Karimi P / 2014 / Gastric cancer : descriptive epidemiology, risk factors, screening, and prevention / Cancer Epidemiol Biomarkers Prev 23:700~713
정규원 / 2017 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2014 / Cancer Research and Treatment 49(2):292~305
Tsukuma H / 2000 / Natural history of early gastric cancer : a non-concurrent, long term, follow up study / Gut 47:618~621
Yoon Gwon Mun / 2018 / Factors Affecting Endoscopic Curative Resection of Gastric Cancer in the Population-based Screening Era / Clinical Endoscopy 51(5):478~484
강기주 / 2010 / 한국인 위암의 특성 - 조기위암 증가를 중심으로 / 대한의사협회지 53(4):283~289
정규원 / 2017 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2014 / Cancer Research and Treatment 49(2):292~305
Tsukuma H / 2000 / Natural history of early gastric cancer : a non-concurrent, long term, follow up study / Gut 47:618~621
Yoon Gwon Mun / 2018 / Factors Affecting Endoscopic Curative Resection of Gastric Cancer in the Population-based Screening Era / Clinical Endoscopy 51(5):478~484
강기주 / 2010 / 한국인 위암의 특성 - 조기위암 증가를 중심으로 / 대한의사협회지 53(4):283~289
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