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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 108 - 116 (9page)
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초록· 키워드
오류제보하기
With recent advances in fetal medicine, various attempts have been made to save fetuses facing perinatal death ordevastating consequences despite optimal management after birth. The concept of the fetus as a patient has beenestablished through the application of in utero treatments. This paper reviews fetal therapies in order to highlightthe role of perinatal medicine as standard prenatal care. Fetal therapies consist of medical therapy, percutaneousultrasound-guided surgery, fetoscopic surgery, and open fetal surgery. In the 1980s, with advances in ultrasoundimaging, percutaneous ultrasound-guided surgeries such as vesicoamniotic shunting for lower urinary tractobstruction and thoracoamniotic shunting (TAS) for fetal hydrothorax (FHT) were started. In the 1990s, fetoscopiclaser surgery (FLS) for twin-twin transfusion syndrome (TTTS) was introduced, and later, a fetoscopic approach forcongenital diaphragmatic hernia was also established. The revival of open fetal surgery, introduced in the 1980s bypediatric surgeons, began in the 2010s after a successful clinical study for myelomeningocele. Although many fetaltherapies are still considered experimental, some have proven effective, such as FLS for TTTS, TAS for primary FHT, andradiofrequency ablation (RFA) for twin reversed arterial perfusion (TRAP) sequence. These three fetal therapies havebeen approved for coverage by Japan National Health Insurance as a result of clinical studies performed in Japan. FLS for TTTS, TAS for primary FHT, and RFA for TRAP sequence have become standard prenatal care approaches inJapan. These three minimally invasive fetal therapies will help improve the perinatal outcomes of fetuses with thesedisorders.
목차
등록된 정보가 없습니다.
참고문헌 (58)
참고문헌 신청
Liley AW / 1963 / Intrauterine transfusion of foetus in haemolytic disease / BMJ 2:1107~1109
Bang J / 1982 / Ultrasound-guided fetal intravenous transfusion for severe rhesus haemolytic disease / Br Med J(Clin Res Ed) 284:373~374
Golbus MS / 1982 / In utero treatment of urinary tract obstruction / Am J Obstet Gynecol 142:383~388
Rodeck CH / 1988 / Long-term in utero drainage of fetal hydrothorax / N Engl J Med 319:1135~1138
Crombleholme TM / 1988 / Early experience with open fetal surgery for congenital hydronephrosis / J Pediatr Surg 23:1114~1121
Bang J / 1982 / Ultrasound-guided fetal intravenous transfusion for severe rhesus haemolytic disease / Br Med J(Clin Res Ed) 284:373~374
Golbus MS / 1982 / In utero treatment of urinary tract obstruction / Am J Obstet Gynecol 142:383~388
Rodeck CH / 1988 / Long-term in utero drainage of fetal hydrothorax / N Engl J Med 319:1135~1138
Crombleholme TM / 1988 / Early experience with open fetal surgery for congenital hydronephrosis / J Pediatr Surg 23:1114~1121
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