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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 153 - 160 (8page)
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초록· 키워드
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Background: This study aims to examine the association between alcohol consumption and the risk of pre- or type 2 diabetes mellitus (T2DM) by alcohol-induced flushing response in Korean male adults, particularly based on their body mass index (BMI). Methods: This study selected 1,030 (158 non-drinkers, 364 flushers, and 508 non-flushers) male adults who had medical checkups. A logistic regression analysis was used to compare the association between alcohol consumption and the risk of pre- or T2DM. Results: In both the normal-weight group (BMI <23 kg/m2) and the overweight group (BMI ≥23 kg/m2 and <25 kg/ m2), the flushers had a higher risk of pre- or T2DM (odds ratio, 95% confidence interval) when consuming more than 8 drinks of alcohol per week than the non-drinkers (normal-weight group: 3.43, 1.06–11.07; overweight group: 4.94, 1.56–15.67). But in the non-flushers among the normal-weight group and the overweight group, there was no significant difference compared to non-drinkers regarding the risk of pre- or T2DM. Obese flushers had a significantly higher risk of pre- or T2DM when consuming more than 4 drinks of alcohol per week than the non-drinkers (>4 and ≤8 drinks: 2.64, 1.10–6.36; >8 drinks: 2.42, 1.11–5.27). However, obese non-flushers had only a significant higher risk of pre- or T2DM when consuming more than 8 drinks of alcohol per week than the non-drinkers (2.72, 1.39–5.30) Conclusion: These results suggest that obese flushers have an increased risk of developing pre- or T2DM even with less alcohol consumption.
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참고문헌 (28)
참고문헌 신청
Wolff PH / 1972 / Ethnic differences in alcohol sensitivity / Science 175:449~450
Crabb DW / 1995 / Ethanol oxidizing enzymes : roles in alcohol metabolism and alcoholic liver disease / Prog Liver Dis 13:151~172
Agarwal DP / 1981 / Racial differences in biological sensitivity to ethanol : the role of alcohol dehydrogenase and aldehyde dehydrogenase isozymes / Alcohol Clin Exp Res 5:12~16
Jung JG / 2014 / Hypertension associated with alcohol consumption based on the facial flushing reaction to drinking / Alcohol Clin Exp Res 38:1020~1025
김민영 / 2012 / Relationship between Alcohol Consumption and Metabolic Syndrome according to Facial Flushing in Korean Males / Korean Journal of Family Medicine 33(4):211~218
Crabb DW / 1995 / Ethanol oxidizing enzymes : roles in alcohol metabolism and alcoholic liver disease / Prog Liver Dis 13:151~172
Agarwal DP / 1981 / Racial differences in biological sensitivity to ethanol : the role of alcohol dehydrogenase and aldehyde dehydrogenase isozymes / Alcohol Clin Exp Res 5:12~16
Jung JG / 2014 / Hypertension associated with alcohol consumption based on the facial flushing reaction to drinking / Alcohol Clin Exp Res 38:1020~1025
김민영 / 2012 / Relationship between Alcohol Consumption and Metabolic Syndrome according to Facial Flushing in Korean Males / Korean Journal of Family Medicine 33(4):211~218
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