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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
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- 대한소아소화기영양학회 Pediatric Gastroenterology, Hepatology & Nutrition Pediatric Gastroenterology, Hepatology & Nutrition 제23권 제2호
- 발행연도
- 2020.1
- 수록면
- 132 - 136 (5page)
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Purpose: To evaluate the effect of gluten-free diet (GFD) on hepatitis B surface antibody (HBsAb) concentrations among previously immunized pediatric celiac disease (CD) subjects. Methods: We retrospectively evaluated pediatric CD subjects in serological remission who were previously immunized for hepatitis B virus as infants. The temporal relationship between HBsAb concentration, the amount of time on a GFD, and age were evaluated. Results: Overall, 373 CD subjects were analyzed: 156 with HBsAb sampled prior to GFD initiation and 217 after initiation of a GFD and in serological remission. Median age at HBsAb concentration measurement for those before and after GFD initiation was 5.3 years (interquartile range [IQR], 3.1–9.2 years) and 7.6 years (IQR, 5.4–10.9 years), respectively (p<0.001). There was no sex difference between the groups. The median time of HBsAb measurement was 2 months (IQR, 0–5.7 months) before and 12.8 months (IQR, 5.3–30.3 months) after initiation of GFD. The HBsAb concentration was low in 79 (50.6%) and 121 (55.7%) subjects before and after GFD initiation, respectively (p=0.350). Age was inversely associated with low HBsAb concentrations. Neither being on a GFD nor sex was associated with low HBsAb concentrations. Conclusion: Adherence to a GFD does not affect HBsAb concentration in children with CD. Age is inversely associated with HBsAb concentration.
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참고문헌 (16)
참고문헌 신청
Singh P / 2018 / Global prevalence of celiac disease : systematic review and meta-analysis / Clin Gastroenterol Hepatol 16:823~836
Sansotta N / 2018 / Celiac disease symptom resolution : effectiveness of the gluten-free diet / J Pediatr Gastroenterol Nutr 66:48~52
Green PH / 2015 / Clinical manifestations of celiac disease / Dig Dis 33:137~140
Hadler SC / 1986 / Long-term immunogenicity and efficacy of hepatitis B vaccine in homosexual men / N Engl J Med 315:209~214
Schillie S / 2013 / Centers for Disease Control and Prevention (CDC). CDC guidance for evaluating health-care personnel for hepatitis B virus protection and for administering postexposure management / MMWR Recomm Rep 62(RR-10):1~19
Sansotta N / 2018 / Celiac disease symptom resolution : effectiveness of the gluten-free diet / J Pediatr Gastroenterol Nutr 66:48~52
Green PH / 2015 / Clinical manifestations of celiac disease / Dig Dis 33:137~140
Hadler SC / 1986 / Long-term immunogenicity and efficacy of hepatitis B vaccine in homosexual men / N Engl J Med 315:209~214
Schillie S / 2013 / Centers for Disease Control and Prevention (CDC). CDC guidance for evaluating health-care personnel for hepatitis B virus protection and for administering postexposure management / MMWR Recomm Rep 62(RR-10):1~19
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