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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 129 - 145 (17page)
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Objectives: To examine the direct effects of risk factors associated with the 5-year costs of care in persons with alcohol use disorder (AUD) and to examine whether remission decreases the costs of care. Methods: Based on Electronic Health Record data collected in the North Karelia region in Finland from 2012 to 2016, we built a non-causal augmented naïve Bayesian (ANB) network model to examine the directional relationship between 16 risk factors and the costs of care for a random cohort of 363 AUD patients. Jouffe’s proprietary likelihood matching algorithm and van der Weele’s disjunctive confounder criteria (DCC) were used to calculate the direct effects of the variables, and sensitivity analysis with tornado diagrams and analysis maximizing/minimizing the total cost of care were conducted. Results: The highest direct effect on the total cost of care was observed for a number of chronic conditions, indicating on average more than a €26,000 increase in the 5-year mean cost for individuals with multiple ICD-10 diagnoses compared to individuals with less than two chronic conditions. Remission had a decreasing effect on the total cost accumulation during the 5-year follow-up period; the percentage of the lowest cost quartile (42.9% vs. 23.9%) increased among remitters, and that of the highest cost quartile (10.71% vs. 26.27%) decreased compared with current drinkers. Conclusions: The ANB model with application of DCC identified that remission has a favorable causal effect on the total cost accumulation. A high number of chronic conditions was the main contributor to excess cost of care, indicating that comorbidity is an essential mediator of cost accumulation in AUD patients.
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참고문헌 (30)
참고문헌 신청
Dennis M / 2007 / Managing addiction as a chronic condition / Addict Sci Clin Pract 4(1):45~55
Witkiewitz K / 2007 / Modeling the complexity of post-treatment drinking : it's a rocky road to relapse / Clin Psychol Rev 27(6):724~738
National Institute on Alcohol Abuse and Alcoholism / Alcohol facts and statistics
Effertz T / 2013 / The burden and cost of disorders of the brain in Europe with the inclusion of harmful alcohol use and nicotine addiction / Eur Neuropsychopharmacol 23(7):742~748
Gustavsson A / 2011 / Cost of disorders of the brain in Europe 2010 / Eur Neuropsychopharmacol 21(10):718~779
Witkiewitz K / 2007 / Modeling the complexity of post-treatment drinking : it's a rocky road to relapse / Clin Psychol Rev 27(6):724~738
National Institute on Alcohol Abuse and Alcoholism / Alcohol facts and statistics
Effertz T / 2013 / The burden and cost of disorders of the brain in Europe with the inclusion of harmful alcohol use and nicotine addiction / Eur Neuropsychopharmacol 23(7):742~748
Gustavsson A / 2011 / Cost of disorders of the brain in Europe 2010 / Eur Neuropsychopharmacol 21(10):718~779
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