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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제16권 제3호
- 발행연도
- 2018.1
- 수록면
- 267 - 275 (9page)
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초록· 키워드
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Objective: Externalizing disorders such as attention-deficit/hyperactivity disorder (ADHD), conduct disorder and antisocial personality disorder, as well as depression are common comorbidities in alcohol use disorder (AUD). The current study focused on the temporal relationship between the onsets of these disorders and AUD, and investigated the serial multiple mediator model of externalizing disorders (e.g., ADHD) and depression on AUD. Methods: We analyzed the mediated effects of the Adult ADHD Self-Report Scale (ASRS), the Barratt Impulsiveness Scale motor (BIS_M) and the Beck Depression Inventory (BDI) on Korean version of the Alcohol Dependence Scale (ADS_K) using the multiple-step multiple mediation procedure regression analysis. In addition, we comparatively analyzed different clinical characteristics in relation to conduct problems. Results: The multiple-step multiple mediation procedure found the serial multiple mediated effects of the BIS_M and the BDI on the relationship between the ASRS and the ADS_K. Also, the group with conduct problem was significantly high in ADHD symptoms, depression, anxiety, impulsivity, legal problems and alcohol-related problems, compared to the group without conduct problems. Conclusion: To sum up, the results of this study show that ADHD symptoms in childhood could exert significant effects on the severity of AUD in adulthood, and both disorders might be mediated by the externalizing disorders characterized by the core feature of motor impulsivity, and depression serially. Thus, the treatment of preceding disorders in accordance with developmental stages is an overarching clinical component for preventing the subsequent development of AUD and for its treatment.
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등록된 정보가 없습니다.
참고문헌 (44)
참고문헌 신청
Kessler RC / 2005 / Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication / Arch Gen Psychiatry 62:593~602
Kessler RC / 1997 / Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the National Comorbidity Survey / Arch Gen Psychiatry 54:313~321
Kim JW / 2006 / Clinical and genetic characteristics of Korean male alcoholics with and without attention deficit hyperactivity disorder / Alcohol Alcohol 41:407~411
Biederman J / 1995 / Psychoactive substance use disorders in adults with attention deficit hyperactivity disorder (ADHD): effects of ADHD and psychiatric comorbidity / Am J Psychiatry 152:1652~1658
Lee SS / 2011 / Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: a meta-analytic review / Clin Psychol Rev 31:328~341
Kessler RC / 1997 / Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the National Comorbidity Survey / Arch Gen Psychiatry 54:313~321
Kim JW / 2006 / Clinical and genetic characteristics of Korean male alcoholics with and without attention deficit hyperactivity disorder / Alcohol Alcohol 41:407~411
Biederman J / 1995 / Psychoactive substance use disorders in adults with attention deficit hyperactivity disorder (ADHD): effects of ADHD and psychiatric comorbidity / Am J Psychiatry 152:1652~1658
Lee SS / 2011 / Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: a meta-analytic review / Clin Psychol Rev 31:328~341
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