지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.6
- 수록면
- 129 - 134 (6page)
- DOI
- 10.7841/ksbbj.2020.35.2.129
이용수
초록· 키워드
오류제보하기
Lactic acid is widely used in the food, pharmaceutical, textile and chemical industries. Also, poly-lactic acid (PLA) is in increasing demand as an environmentally friendly and biodegradable plastic. In our prior study, a lactic acid-producing, xylose-fermenting Saccharomyces cerevisiae strain (SR8 LDH) has been developed. In the present study, we tested the SR8 LDH strain under various fermentation conditions to discover the most important condition determining lactic acid and ethanol production profiles. Using xylose as a substrate significantly improved lactic acid yields compared to using glucose under microaerobic conditions. High initial cell density improved lactic acid productivity, but it did not affect ethanol production. Lastly, when fermenting xylose, the PDC1 gene encoding pyruvate decarboxylase was transcriptionally repressed, which might be associated with the production of low ethanol and high lactic acid. These results indicate that the type of a carbon source, i.e. using xylose instead of glucose could be a promising solution for lactic acid production by engineered S. cerevisiae.
목차
Abstract
1. INTRODUCTION
2. MATERIALS AND METHODS
3. RESULTS AND DISCUSSION
4. CONCLUSION
REFERENCES
참고문헌 (22)
참고문헌 신청
Esteban, J. / 2018 / Food waste as a source of valueadded chemicals and materials : a biorefinery perspective / Int. J. Food Sci. Technol 53:1095~1108
Bustamante, D. / 2020 / Production of D-Lactic Acid by the Fermentation of Orange Peel Waste Hydrolysate by Lactic Acid Bacteria / Fermentation 6:1
Jamshidian, M. / 2010 / Poly-Lactic Acid : production, applications, nanocomposites, and release studies / Compr. Rev. Food. Sci. Food Saf 9:552~571
Singhvi, M. / 2019 / Poly-Lactic acid(PLA) : synthesis and biomedical applications / J. Appl. Microbiol 127:1612~1626
Sauer, M. / 2008 / Microbial production of organic acids : expanding the markets / Trends Biotechnol 26:100~108
Bustamante, D. / 2020 / Production of D-Lactic Acid by the Fermentation of Orange Peel Waste Hydrolysate by Lactic Acid Bacteria / Fermentation 6:1
Jamshidian, M. / 2010 / Poly-Lactic Acid : production, applications, nanocomposites, and release studies / Compr. Rev. Food. Sci. Food Saf 9:552~571
Singhvi, M. / 2019 / Poly-Lactic acid(PLA) : synthesis and biomedical applications / J. Appl. Microbiol 127:1612~1626
Sauer, M. / 2008 / Microbial production of organic acids : expanding the markets / Trends Biotechnol 26:100~108
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UCI(KEPA) : I410-ECN-0101-2020-470-000886982