A Study of Respiratory Syncytial Virus Outbreak at Postpartum Care Center in Busan, Korea

Su-Jeong Hwang; Ho-Cheol Yun; Pyeong-Tae Ku; Ju-Hee Sim; Mi-Ok Lee

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자료유형: 학술저널

저자정보: Su-Jeong Hwang (Busan Metropolitan City Institute of Health & Environment) Ho-Cheol Yun (Busan Metropolitan City Institute of Health & Environment) Pyeong-Tae Ku (Busan Metropolitan City Institute of Health & Environment) Ju-Hee Sim (Busan Metropolitan City Institute of Health & Environment) Mi-Ok Lee (Busan Metropolitan City Institute of Health & Environment)

저널정보: 대한미생물학회 JOURNAL OF BACTERIOLOGY AND VIROLOGY JOURNAL OF BACTERIOLOGY AND VIROLOGY Vol.50 No.2

발행연도: 2020.6

수록면: 124 - 131 (8page)

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Respiratory syncytial virus (RSV) is common cause of acute respiratory infection in infants and young children. Group life in postpartum care centers is easily exposed to infectious diseases in neonates and puerperds immediately after giving birth, and the harm caused by exposure to them is much greater. In particular, respiratory diseases are highly infectious and infections occur in a short period of time. among them, RSV infections are very serious in children under 5 years of age, leading to death. This paper studied an infection of RSV in outbreaks at postpartum care center in Busan. In 4 postpartum care centers, a total of 877 people (390 neonates, 386 puerperds, 106 others) were exposed to RSV outbreak. Of these, there were 73 RSV-positive patients; most of them had cough and runny nose and no fever. We were collected from neonates and puerperds with acute respiratory tract a total of 146 samples (throat swabs). In 51 samples, RSV (43 cases), human rhinovirus (6 cases), human coronavirus NL63 (1 case), and human coronavirus 229E (1 case) were found to be positive and the rest were negative. All 43 RSV positive samples were identified as RSV B. Sequence analysis of the detected strains was performed to confirm the molecular genetic information of RSV. Out of 43 RSV positive samples, 38 samples were successfully sequenced using the G gene, resulting in all of the same genotype BA9. This study provides a better understanding of RSV prevalence patterns and genetic characteristics. It also contributes to the accumulation of epidemiological data and the development of public health and hygiene.

#Respiratory syncytial virus #Postpartum care centers #Molecular typing #Outbreaks

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